Literature DB >> 19303550

Dietary management of obesity and insulin resistance: countering risk for laminitis.

Raymond J Geor1, Patricia Harris.   

Abstract

Insulin resistance (IR) and hyperinsulinemia increase risk for development of laminitis in horses and ponies. Obesity also has been associated with heightened risk for laminitis, likely by means of development of IR. Dietary factors, particularly the nonstructural carbohydrate (NSC) load, modulate risk for laminitis in these animals by means of exacerbation of IR or gastrointestinal disturbances that trigger the condition. Specific dietary management strategies to lessen risk for laminitis include caloric restriction to promote weight loss and improve insulin sensitivity in obese animals and strict control of dietary NSCs, with elimination of grains and sweet feeds from the ration and restricted access to pastures that may be rich in NSCs. Medical treatment with levothyroxine or metformin may be indicated in animals that do not respond to conservative dietary management.

Entities:  

Mesh:

Year:  2009        PMID: 19303550     DOI: 10.1016/j.cveq.2009.02.001

Source DB:  PubMed          Journal:  Vet Clin North Am Equine Pract        ISSN: 0749-0739            Impact factor:   1.792


  14 in total

1.  Naturally occurring compensated insulin resistance selectively alters glucose transporters in visceral and subcutaneous adipose tissues without change in AS160 activation.

Authors:  A P Waller; K Kohler; T A Burns; M C Mudge; J K Belknap; V A Lacombe
Journal:  Biochim Biophys Acta       Date:  2011-02-23

2.  Digestibility and nitrogen and water balance in horses fed rhizoma peanut hay.

Authors:  Ana Caroline C M Vasco; Katy J Brinkley-Bissinger; Jillian M Bobel; José C B Dubeux; Lori K Warren; Carissa L Wickens
Journal:  J Anim Sci       Date:  2021-11-01       Impact factor: 3.338

3.  Relationships among Body Condition, Insulin Resistance and Subcutaneous Adipose Tissue Gene Expression during the Grazing Season in Mares.

Authors:  Shaimaa Selim; Kari Elo; Seija Jaakkola; Ninja Karikoski; Ray Boston; Tiina Reilas; Susanna Särkijärvi; Markku Saastamoinen; Tuomo Kokkonen
Journal:  PLoS One       Date:  2015-05-04       Impact factor: 3.240

Review 4.  A Potential Role for Pro-Inflammatory Cytokines in the Development of Insulin Resistance in Horses.

Authors:  Jessica K Suagee; Benjamin A Corl; Raymond J Geor
Journal:  Animals (Basel)       Date:  2012-05-02       Impact factor: 2.752

5.  Sweet taste receptor inhibitors: Potential treatment for equine insulin dysregulation.

Authors:  Melody Anne de Laat; Murad Hasan Kheder; Christopher Charles Pollitt; Martin Nicholas Sillence
Journal:  PLoS One       Date:  2018-06-29       Impact factor: 3.240

6.  Influence of dietary restriction and low-intensity exercise on weight loss and insulin sensitivity in obese equids.

Authors:  Nicholas J Bamford; Samantha J Potter; Courtnay L Baskerville; Patricia A Harris; Simon R Bailey
Journal:  J Vet Intern Med       Date:  2018-12-05       Impact factor: 3.333

7.  Weight loss is linearly associated with a reduction of the insulin response to an oral glucose test in Icelandic horses.

Authors:  Julien Delarocque; Florian Frers; Korinna Huber; Karsten Feige; Tobias Warnken
Journal:  BMC Vet Res       Date:  2020-05-24       Impact factor: 2.741

8.  Metabolic impact of weight variations in Icelandic horses.

Authors:  Julien Delarocque; Florian Frers; Korinna Huber; Klaus Jung; Karsten Feige; Tobias Warnken
Journal:  PeerJ       Date:  2021-01-28       Impact factor: 2.984

Review 9.  Expression and regulation of facilitative glucose transporters in equine insulin-sensitive tissue: from physiology to pathology.

Authors:  Véronique A Lacombe
Journal:  ISRN Vet Sci       Date:  2014-03-04

Review 10.  Equine pituitary pars intermedia dysfunction: current perspectives on diagnosis and management.

Authors:  Caroline W Spelta
Journal:  Vet Med (Auckl)       Date:  2015-08-20
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