OBJECTIVE: The objective was to extract, quantify and characterize the uterine magnetomyographic (MMG) signals that correspond to the electrophysiological activity of the uterus. METHODS: Transabdominal MMG recordings with high spatial-temporal resolution were performed with the use of the 151 non-invasive magnetic sensor system. The extraction, quantification and characterization procedures were developed and applied to representative MMG signals that were recorded from a pregnant woman at regular intervals starting at 37 weeks of gestation until the subject reached active labor. RESULTS: Multiple MMG recordings were successfully performed on the subject before she went into active labor. The extracted MMG burst activity showed a statistically significant correlation (r=0.2; p<0.001) with the contractile events perceived by mothers. The time-frequency analysis of the burst activity showed a power shift towards higher-frequency at 48 h before the subject went into active labor as compared to earlier recordings. Further there was a gradual increase in the synchrony in the higher-frequency band as the subject reached close to active labor. CONCLUSIONS: The non-invasive recording of the magnetic signals of pregnant uterus with high spatial-temporal resolution can provide an insight into the preparatory phase of labor and has the potential of predicting term and preterm labor.
OBJECTIVE: The objective was to extract, quantify and characterize the uterine magnetomyographic (MMG) signals that correspond to the electrophysiological activity of the uterus. METHODS: Transabdominal MMG recordings with high spatial-temporal resolution were performed with the use of the 151 non-invasive magnetic sensor system. The extraction, quantification and characterization procedures were developed and applied to representative MMG signals that were recorded from a pregnant woman at regular intervals starting at 37 weeks of gestation until the subject reached active labor. RESULTS: Multiple MMG recordings were successfully performed on the subject before she went into active labor. The extracted MMG burst activity showed a statistically significant correlation (r=0.2; p<0.001) with the contractile events perceived by mothers. The time-frequency analysis of the burst activity showed a power shift towards higher-frequency at 48 h before the subject went into active labor as compared to earlier recordings. Further there was a gradual increase in the synchrony in the higher-frequency band as the subject reached close to active labor. CONCLUSIONS: The non-invasive recording of the magnetic signals of pregnant uterus with high spatial-temporal resolution can provide an insight into the preparatory phase of labor and has the potential of predicting term and preterm labor.
Authors: Hari Eswaran; Hubert Preissl; James D Wilson; Pam Murphy; Stephen E Robinson; Curtis L Lowery Journal: Am J Obstet Gynecol Date: 2002-07 Impact factor: 8.661
Authors: Robert E Garfield; William L Maner; Lyn B MacKay; Dietmar Schlembach; George R Saade Journal: Am J Obstet Gynecol Date: 2005-07 Impact factor: 8.661
Authors: R E Garfield; G Saade; C Buhimschi; I Buhimschi; L Shi; S Q Shi; K Chwalisz Journal: Hum Reprod Update Date: 1998 Sep-Oct Impact factor: 15.610
Authors: Diana Escalona-Vargas; Rathinaswamy B Govindan; Adrian Furdea; Pam Murphy; Curtis L Lowery; Hari Eswaran Journal: PLoS One Date: 2015-10-27 Impact factor: 3.240