Literature DB >> 19302965

Molecular biology: an early detector of oral cancers.

Siddiq M Ahmed1, V R Jigna.   

Abstract

Oral cancers have been one of the leading causes of deaths particularly in the developing countries. Prime reason for this high mortality and morbidity is attributed to the delay in diagnosis and prompt treatment. Relentless research in the field of oncology has led to advent of novel procedures for the early detection of oral cancers. Molecular biology is highly promising in this regard. It is a procedure that detects alterations at a molecular level much before they are seen under a microscope and much before clinical changes occur. Molecular studies serve as basis by which we will eventually be able not only to augment clinical assessment and classification of oral lesions but also predict malignant potential of oral lesions, thus reducing incidence and increasing the scope for early diagnosis and treatment of oral cancers. However, making such sophisticated tools available for the common man in developing countries is one of the most important challenges faced today.

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Year:  2009        PMID: 19302965     DOI: 10.1016/j.anndiagpath.2008.12.003

Source DB:  PubMed          Journal:  Ann Diagn Pathol        ISSN: 1092-9134            Impact factor:   2.090


  5 in total

1.  Evaluation and Comparison of Genomic DNA Extraction Methods and PCR Optimization on Archival Formalin-Fixed and Paraffin-Embedded Tissues of Oral Squamous Cell Carcinoma.

Authors:  Samar Saeed Khan; Manisha Tijare; Sowmya Kasetty; Megha Jain; Ahmed Alamoudi; Hammam Ahmed Bahammam; Sarah Ahmed Bahammam; Maha A Bahammam; Saranya Varadarajan; A Thirumal Raj; Shankargouda Patil
Journal:  Diagnostics (Basel)       Date:  2022-05-12

2.  Molecular predictors in the early diagnosis of oral cancer.

Authors:  S Rajkumari; J Sathiyajeeva; C Santhosh Kumar; P M Sunil; B Thayumanavan
Journal:  J Clin Diagn Res       Date:  2013-03-21

3.  Quantitative risk stratification of oral leukoplakia with exfoliative cytology.

Authors:  Yao Liu; Jianying Li; Xiaoyong Liu; Xudong Liu; Waqaar Khawar; Xinyan Zhang; Fan Wang; Xiaoxin Chen; Zheng Sun
Journal:  PLoS One       Date:  2015-05-15       Impact factor: 3.240

4.  Quantitative prediction of oral cancer risk in patients with oral leukoplakia.

Authors:  Yao Liu; Yicheng Li; Yue Fu; Tong Liu; Xiaoyong Liu; Xinyan Zhang; Jie Fu; Xiaobing Guan; Tong Chen; Xiaoxin Chen; Zheng Sun
Journal:  Oncotarget       Date:  2017-07-11

Review 5.  Role of proteomics in physiologic and pathologic conditions of dentistry: Overview.

Authors:  Thukanayakanpalayam Ragunathan Yoithapprabhunath; Ramadas Madhavan Nirmal; Arumugam Santhadevy; Abraham Anusushanth; Duraisamy Charanya; K K Sri Chinthu; Andamuthu Yamunadevi
Journal:  J Pharm Bioallied Sci       Date:  2015-08
  5 in total

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