Literature DB >> 19300911

Dose-dependent RNAi-mediated geminivirus resistance in the tropical root crop cassava.

Hervé Vanderschuren1, Adrian Alder, Peng Zhang, Wilhelm Gruissem.   

Abstract

Cassava mosaic disease is a major constraint for cassava production in Africa, resulting in significant economic losses. We have engineered transgenic cassava with resistance to African cassava mosaic virus (ACMV), by expressing ACMV AC1-homologous hairpin double-strand RNAs. Transgenic cassava lines with high levels of AC1-homologous small RNAs have ACMV immunity with increasing viral load and different inoculation methods. We report a correlation between the expression of the AC1-homologous small RNAs and the ACMV resistance of the transgenic cassava lines. Characterization of the small RNAs revealed that only some of the hairpin-derived small RNAs fall into currently known small interfering RNA classes in plants. The method is scalable to stacking by targeting multiple virus isolates with additional hairpins.

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Year:  2009        PMID： 19300911     DOI： 10.1007/s11103-009-9472-3

Source DB:  PubMed          Journal:  Plant Mol Biol        ISSN： 0167-4412            Impact factor:   4.076


  34 in total

Review 1.  Geminiviruses: models for plant DNA replication, transcription, and cell cycle regulation.

Authors:  L Hanley-Bowdoin; S B Settlage; B M Orozco; S Nagar; D Robertson
Journal:  Crit Rev Biochem Mol Biol       Date:  2000       Impact factor: 8.250

2.  Geminivirus disease complexes: the threat is spreading.

Authors:  Shahid Mansoor; Yusuf Zafar; Rob W Briddon
Journal:  Trends Plant Sci       Date:  2006-04-17       Impact factor: 18.313

3.  Resistance to tomato yellow leaf curl geminivirus in Nicotiana benthamiana plants transformed with a truncated viral C1 gene.

Authors:  E Noris; G P Accotto; R Tavazza; A Brunetti; S Crespi; M Tavazza
Journal:  Virology       Date:  1996-10-01       Impact factor: 3.616

4.  Two classes of endogenous small RNAs in Tetrahymena thermophila.

Authors:  Suzanne R Lee; Kathleen Collins
Journal:  Genes Dev       Date:  2005-12-15       Impact factor: 11.361

5.  Broad spectrum resistance to ssDNA viruses associated with transgene-induced gene silencing in cassava.

Authors:  Padmanabhan Chellappan; Munyaradzi V Masona; Ramachandran Vanitharani; Nigel J Taylor; Claude M Fauquet
Journal:  Plant Mol Biol       Date:  2004-11       Impact factor: 4.076

6.  Maize streak virus-resistant transgenic maize: a first for Africa.

Authors:  Dionne N Shepherd; Tichaona Mangwende; Darren P Martin; Marion Bezuidenhout; Frederik J Kloppers; Charlene H Carolissen; Adérito L Monjane; Edward P Rybicki; Jennifer A Thomson
Journal:  Plant Biotechnol J       Date:  2007-11       Impact factor: 9.803

7.  RNAi-mediated resistance to Bean golden mosaic virus in genetically engineered common bean (Phaseolus vulgaris).

Authors:  Kenny Bonfim; Josias C Faria; Elsa O P L Nogueira; Erica A Mendes; Francisco J L Aragão
Journal:  Mol Plant Microbe Interact       Date:  2007-06       Impact factor: 4.171

8.  Production of siRNA targeted against TYLCV coat protein transcripts leads to silencing of its expression and resistance to the virus.

Authors:  Avi Zrachya; Pravin P Kumar; Usha Ramakrishnan; Yael Levy; Abraham Loyter; Tzahi Arazi; Moshe Lapidot; Yedidya Gafni
Journal:  Transgenic Res       Date:  2006-11-14       Impact factor: 3.145

9.  Intron-hairpin RNA derived from replication associated protein C1 gene confers immunity to tomato yellow leaf curl virus infection in transgenic tomato plants.

Authors:  Alejandro Fuentes; Pedro L Ramos; Elvira Fiallo; Danay Callard; Yadira Sánchez; Rudy Peral; Raidel Rodríguez; Merardo Pujol
Journal:  Transgenic Res       Date:  2006-06       Impact factor: 3.145

10.  Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing.

Authors:  Todd Blevins; Rajendran Rajeswaran; Padubidri V Shivaprasad; Daria Beknazariants; Azeddine Si-Ammour; Hyun-Sook Park; Franck Vazquez; Dominique Robertson; Frederick Meins; Thomas Hohn; Mikhail M Pooggin
Journal:  Nucleic Acids Res       Date:  2006-11-07       Impact factor: 16.971
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  39 in total

1.  Agrobacterium-mediated transformation of friable embryogenic calli and regeneration of transgenic cassava.

Authors:  S E Bull; J A Owiti; M Niklaus; J R Beeching; W Gruissem; H Vanderschuren
Journal:  Nat Protoc       Date:  2009       Impact factor: 13.491

2.  A sweetpotato SRD1 promoter confers strong root-, taproot-, and tuber-specific expression in Arabidopsis, carrot, and potato.

Authors:  Seol Ah Noh; Haeng-Soon Lee; Gyung Hye Huh; Mi-Joung Oh; Kyung-Hee Paek; Jeong Sheop Shin; Jung Myung Bae
Journal:  Transgenic Res       Date:  2011-06-10       Impact factor: 2.788

3.  Strategy for a generic resistance to geminiviruses infecting tomato and papaya through in silico siRNA search.

Authors:  Sangeeta Saxena; Nidhi Singh; S A Ranade; Sunil G Babu
Journal:  Virus Genes       Date:  2011-08-06       Impact factor: 2.332

4.  Identification of siRNA generating hot spots in multiple viral suppressors to generate broad-spectrum antiviral resistance in plants.

Authors:  Veerendra Kumar Sharma; Nirbhay Kushwaha; Saumik Basu; Ashish Kumar Singh; Supriya Chakraborty
Journal:  Physiol Mol Biol Plants       Date:  2014-10-10

5.  Transgenic tobacco plants expressing siRNA targeted against the Mungbean yellow mosaic virus transcriptional activator protein gene efficiently block the viral DNA accumulation.

Authors:  Gnanasekaran Shanmugapriya; Sudhanshu Sekhar Das; Karuppannan Veluthambi
Journal:  Virusdisease       Date:  2015-04-18

6.  Mungbean yellow mosaic virus (MYMV) AC4 suppresses post-transcriptional gene silencing and an AC4 hairpin RNA gene reduces MYMV DNA accumulation in transgenic tobacco.

Authors:  Sukumaran Sunitha; Gnanasekaran Shanmugapriya; Veluthambi Balamani; Karuppannan Veluthambi
Journal:  Virus Genes       Date:  2013-02-17       Impact factor: 2.332

7.  Hairpin transcription does not necessarily lead to efficient triggering of the RNAi pathway.

Authors:  Athanasios Dalakouras; Maria Tzanopoulou; Mina Tsagris; Michael Wassenegger; Kriton Kalantidis
Journal:  Transgenic Res       Date:  2010-06-26       Impact factor: 2.788

Review 8.  Cassava: constraints to production and the transfer of biotechnology to African laboratories.

Authors:  Simon E Bull; Joseph Ndunguru; Wilhelm Gruissem; John R Beeching; Hervé Vanderschuren
Journal:  Plant Cell Rep       Date:  2011-01-07       Impact factor: 4.570

Review 9.  A molecular insight into papaya leaf curl-a severe viral disease.

Authors:  Priyanka Varun; S A Ranade; Sangeeta Saxena
Journal:  Protoplasma       Date:  2017-05-25       Impact factor: 3.356

10.  Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration.

Authors:  Hervé Vanderschuren; Evans Nyaboga; Jacquelyne S Poon; Katja Baerenfaller; Jonas Grossmann; Matthias Hirsch-Hoffmann; Norbert Kirchgessner; Paolo Nanni; Wilhelm Gruissem
Journal:  Plant Cell       Date:  2014-05-29       Impact factor: 11.277
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