Myeloma of the eyelid: a rare necrotizing lesion.

A 77-year-old man was referred to the authors with an impression of recurrent chalazion of the left lower eyelid. He had suffered from multiple myeloma and had undergone chemotherapy for 11 months. A 2.0 x 0.8 cm, firm, tender, oval-shaped, ulcerated mass with an accompanying black crust on its surface, and erythematous swelling around it was observed. Evaluation of an eyelid biopsy specimen revealed neoplastic plasma cells with eccentric nuclei and monoclonality for lambda light chain, which the authors report as the first case of metastatic multiple myeloma presenting as a rare necrotizing eyelid lesion.