Literature DB >> 19299521

Both a protective and a deleterious role for the L76V mutation.

Alessandra Tartaglia, Annalisa Saracino, Laura Monno, Carmine Tinelli, Gioacchino Angarano.   

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Year:  2009        PMID： 19299521      PMCID： PMC2663083          DOI： 10.1128/AAC.01693-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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  5 in total

1.  Prevalence and impact of HIV-1 protease mutation L76V on lopinavir resistance.

Authors:  Carmen de Mendoza; Carolina Garrido; Angélica Corral; Natalia Zahonero; Vincent Soriano
Journal:  AIDS       Date:  2008-01-11       Impact factor: 4.177

2.  Update of the drug resistance mutations in HIV-1: Spring 2008.

Authors:  Victoria A Johnson; Françoise Brun-Vezinet; Bonaventura Clotet; Huldrych F Günthard; Daniel R Kuritzkes; Deenan Pillay; Jonathan M Schapiro; Douglas D Richman
Journal:  Top HIV Med       Date:  2008 Apr-May

3.  Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir.

Authors:  John D Baxter; Jonathan M Schapiro; Charles A B Boucher; Veronika M Kohlbrenner; David B Hall; Joseph R Scherer; Douglas L Mayers
Journal:  J Virol       Date:  2006-08-23       Impact factor: 5.103

4.  Factors associated with the selection of mutations conferring resistance to protease inhibitors (PIs) in PI-experienced patients displaying treatment failure on darunavir.

Authors:  Sidonie Lambert-Niclot; Philippe Flandre; Ana Canestri; Gilles Peytavin; Christine Blanc; Rachid Agher; Cathia Soulié; Marc Wirden; Christine Katlama; Vincent Calvez; Anne-Geneviève Marcelin
Journal:  Antimicrob Agents Chemother       Date:  2007-11-26       Impact factor: 5.191

5.  Resistance profile of darunavir: combined 24-week results from the POWER trials.

Authors:  Sandra de Meyer; Tony Vangeneugden; Ben van Baelen; Els de Paepe; Herwig van Marck; Gaston Picchio; Eric Lefebvre; Marie-Pierre de Béthune
Journal:  AIDS Res Hum Retroviruses       Date:  2008-03       Impact factor: 2.205
  5 in total
  4 in total

1.  Prevalence, mutation patterns, and effects on protease inhibitor susceptibility of the L76V mutation in HIV-1 protease.

Authors:  Thomas P Young; Neil T Parkin; Eric Stawiski; Tami Pilot-Matias; Roger Trinh; Dale J Kempf; Michael Norton
Journal:  Antimicrob Agents Chemother       Date:  2010-08-30       Impact factor: 5.191

2.  Characterizing Protein-Ligand Binding Using Atomistic Simulation and Machine Learning: Application to Drug Resistance in HIV-1 Protease.

Authors:  Troy W Whitfield; Debra A Ragland; Konstantin B Zeldovich; Celia A Schiffer
Journal:  J Chem Theory Comput       Date:  2020-01-16       Impact factor: 6.006

3.  The L76V drug resistance mutation decreases the dimer stability and rate of autoprocessing of HIV-1 protease by reducing internal hydrophobic contacts.

Authors:  John M Louis; Ying Zhang; Jane M Sayer; Yuan-Fang Wang; Robert W Harrison; Irene T Weber
Journal:  Biochemistry       Date:  2011-05-03       Impact factor: 3.162

4.  Description of the L76V resistance protease mutation in HIV-1 B and "non-B" subtypes.

Authors:  Charlotte Charpentier; Sidonie Lambert-Niclot; Claudia Alteri; Alexandre Storto; Philippe Flandre; Valentina Svicher; Carlo-Federico Perno; Françoise Brun-Vézinet; Vincent Calvez; Anne-Geneviève Marcelin; Francesca Ceccherini-Silberstein; Diane Descamps
Journal:  PLoS One       Date:  2013-01-18       Impact factor: 3.240
  4 in total

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