| Literature DB >> 19299129 |
Daniele Castagnolo1, Marco Radi, Filippo Dessì, Fabrizio Manetti, Manuela Saddi, Rita Meleddu, Alessandro De Logu, Maurizio Botta.
Abstract
A series of novel enantiomerically pure azole derivatives was synthesized. The new compounds, bearing both an imidazole as well as a triazole moiety, were evaluated as antimycobacterial agents. One of them proved to have activity against Mycobaterium tuberculosis comparable to those of the classical antibacterial/antifungal drugs Econazole and Clotrimazole.Entities:
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Year: 2009 PMID： 19299129 DOI： 10.1016/j.bmcl.2009.02.101
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823