OBJECTIVES: To evaluate a Chinese version of the Non-Motor Symptoms Scale (NMSS) in Parkinson's disease (PD) as an instrument for measuring non-motor symptoms (NMSs) in Chinese patients with Parkinson's disease. METHODS: We conducted a psychometric analysis of the Chinese version of NMSS using a cross-sectional study of 126 patients with PD. The battery also included the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Mini-Mental State Examination (MMSE), the Geriatric Depression Scale (GDS), and the Hamilton Anxiety Scale (HAMA), and was conducted by neurologists. RESULTS: There were significant correlations between the NMSS and PSQI scores (rS=0.63, P<0.001), as well as the NMSS and ESS scores (rS=0.38, P<0.001). Furthermore, significant positive correlations between NMSS and GDS, NMSS and HAMA, and NMSS and disease duration were also observed. Importantly, the sleep/fatigue index of the NMSS significantly correlated with the PSQI and ESS findings, the mood/cognition index of the NMSS significantly correlated with the GDS and HAMA findings, and the attention/memory index of the NMSS significantly correlated with the MMSE findings. CONCLUSION: The Chinese version of the NMSS can be considered a comprehensive, useful measure for NMS evaluation in Chinese PD patients.
OBJECTIVES: To evaluate a Chinese version of the Non-Motor Symptoms Scale (NMSS) in Parkinson's disease (PD) as an instrument for measuring non-motor symptoms (NMSs) in Chinese patients with Parkinson's disease. METHODS: We conducted a psychometric analysis of the Chinese version of NMSS using a cross-sectional study of 126 patients with PD. The battery also included the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Mini-Mental State Examination (MMSE), the Geriatric Depression Scale (GDS), and the Hamilton Anxiety Scale (HAMA), and was conducted by neurologists. RESULTS: There were significant correlations between the NMSS and PSQI scores (rS=0.63, P<0.001), as well as the NMSS and ESS scores (rS=0.38, P<0.001). Furthermore, significant positive correlations between NMSS and GDS, NMSS and HAMA, and NMSS and disease duration were also observed. Importantly, the sleep/fatigue index of the NMSS significantly correlated with the PSQI and ESS findings, the mood/cognition index of the NMSS significantly correlated with the GDS and HAMA findings, and the attention/memory index of the NMSS significantly correlated with the MMSE findings. CONCLUSION: The Chinese version of the NMSS can be considered a comprehensive, useful measure for NMS evaluation in Chinese PDpatients.
Authors: Donald M Kuhn; Catherine E Sykes; Timothy J Geddes; Karen L Eskow Jaunarajs; Christopher Bishop Journal: J Neurochem Date: 2010-12-13 Impact factor: 5.372
Authors: Seong-Beom Koh; Jae Woo Kim; Hyeo-Il Ma; Tae-Beom Ahn; Jin Whan Cho; Phil Hyu Lee; Sun Ju Chung; Joong-Seok Kim; Do Young Kwon; Jong Sam Baik Journal: J Clin Neurol Date: 2012-12-21 Impact factor: 3.077