Wenjing Zhang1, Zhilan Peng, Lian Xu. 1. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Abstract
BACKGROUND: Extragastrointestinal stromal tumor (EGIST) is a rare tumor that shows features of gastrointestinal stromal tumor (GIST) outside the gastrointestinal tract, but EGIST arising in the rectovaginal septum is extremely rare. CASE: We report a unique case of a 42-year-old woman with EGIST in rectovaginal septum. The tumor was excised locally. The patient is healthy without evidence of recurrence 11 months after surgery. CONCLUSION: The clinical features and treatment of EGIST are not well known because few cases have been reported. Pathologically, immunohistochemistry with antibody against c-kit protein (CD117) is valuable for diagnosis of EGIST. Mitotic rate is the most reliable prognostic factor, and mutations in KIT may be a clinically useful adjunct marker in the evaluation. Surgery is the most effective treatment, and long-term follow-up is necessary.
BACKGROUND:Extragastrointestinal stromal tumor (EGIST) is a rare tumor that shows features of gastrointestinal stromal tumor (GIST) outside the gastrointestinal tract, but EGIST arising in the rectovaginal septum is extremely rare. CASE: We report a unique case of a 42-year-old woman with EGIST in rectovaginal septum. The tumor was excised locally. The patient is healthy without evidence of recurrence 11 months after surgery. CONCLUSION: The clinical features and treatment of EGIST are not well known because few cases have been reported. Pathologically, immunohistochemistry with antibody against c-kit protein (CD117) is valuable for diagnosis of EGIST. Mitotic rate is the most reliable prognostic factor, and mutations in KIT may be a clinically useful adjunct marker in the evaluation. Surgery is the most effective treatment, and long-term follow-up is necessary.
Authors: Márta Sereg; István Buzogány; Gábor Gonda; Zoltán Sápi; Eva Csöregh; Zsuzsa Jakab; Károly Rácz; Miklós Tóth Journal: Endocrine Date: 2011-02 Impact factor: 3.633
Authors: Alexander W Beham; Inga-Marie Schaefer; Philipp Schüler; Silke Cameron; B Michael Ghadimi Journal: Int J Colorectal Dis Date: 2011-11-29 Impact factor: 2.571