| Literature DB >> 19296671 |
Lin Wang1, Jianxian Gong, Lujiang Deng, Zheng Xiang, Zhixing Chen, Yuefan Wang, Jiahua Chen, Zhen Yang.
Abstract
A novel synthetic approach for the formal total synthesis of N-methylmaysenine (1) has been developed. Key steps involve the Ti-mediated vinylogous Mukaiyama aldol reaction of chiral ketene silyl N,O-acetal with beta-dithiane-substituted aldehyde, an aldol condensation, and a ring-closing metathesis reaction.Entities:
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Year: 2009 PMID： 19296671 DOI： 10.1021/ol900384u
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005