OBJECTIVE: To investigate the potential role of the preventive nutritional support in patients with nutritional risk defined by nutrition risk screening 2002(NRS 2002) before radical resection of gastric cancer. METHODS:Patients with gastric cancer were evaluated by NRS 2002 preoperatively. Elective patients with nutritional risk were randomly assigned into 3 d preventive enteral nutrition(EN) group versus control group. The preventive nutrition regimen was 1000 ml Nutrison Multi Fibre(4184 kJ/L). The changes in body weight lost, serum albumin, immunoglobulin were recorded postoperatively. RESULTS: One week after operation, the preventive EN group showed less decrease in body weight as compared to control group, which was statistically significant. The levels of serum albumin and IgA on day 1 and day 3 after operation in preventive EN group were significantly higher than those in control group. CONCLUSION: Before operation for gastric cancer, patients with nutritional risk defined by NRS 2002 may benefit from preventive enteral nutrition, which improves the patients' nutritional condition and enhances their immunologic function.
RCT Entities:
OBJECTIVE: To investigate the potential role of the preventive nutritional support in patients with nutritional risk defined by nutrition risk screening 2002(NRS 2002) before radical resection of gastric cancer. METHODS:Patients with gastric cancer were evaluated by NRS 2002 preoperatively. Elective patients with nutritional risk were randomly assigned into 3 d preventive enteral nutrition(EN) group versus control group. The preventive nutrition regimen was 1000 ml Nutrison Multi Fibre(4184 kJ/L). The changes in body weight lost, serum albumin, immunoglobulin were recorded postoperatively. RESULTS: One week after operation, the preventive EN group showed less decrease in body weight as compared to control group, which was statistically significant. The levels of serum albumin and IgA on day 1 and day 3 after operation in preventive EN group were significantly higher than those in control group. CONCLUSION: Before operation for gastric cancer, patients with nutritional risk defined by NRS 2002 may benefit from preventive enteral nutrition, which improves the patients' nutritional condition and enhances their immunologic function.
Authors: Stephen R Knight; Ahmad U Qureshi; Thomas M Drake; Marie Carmela M Lapitan; Mayaba Maimbo; Edwin Yenli; Stephen Tabiri; Dhruva Ghosh; Pamela A Kingsley; Sudha Sundar; Catherine Shaw; Apple P Valparaiso; Aneel Bhangu; Peter Brocklehurst; Laura Magill; Dion G Morton; John Norrie; Tracey E Roberts; Evropi Theodoratou; Thomas G Weiser; Sorrel Burden; Ewen M Harrison Journal: Sci Rep Date: 2022-07-21 Impact factor: 4.996