Literature DB >> 19295939

A primary care perspective on keloids.

Steven Davidson1, Nasir Aziz, Rashid M Rashid, Amor Khachemoune.   

Abstract

Keloids are a common presenting complaint in the primary care clinic. This condition presents a formidable challenge, as recurrence is often difficult to prevent despite use of multiple therapeutic interventions. Part of the reason for the absence of a definitive treatment is the incomplete understanding of the pathogenesis of keloid formation, which creates a frustrating situation for both physician and patient. Here we review the most recent literature on the clinical features, pathogenesis, and management of keloids, with special emphasis on the unique challenges faced by primary care physicians.

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Year:  2009        PMID: 19295939      PMCID: PMC2654675     

Source DB:  PubMed          Journal:  Medscape J Med        ISSN: 1934-1997


  61 in total

1.  Hydration, not silicone, modulates the effects of keratinocytes on fibroblasts.

Authors:  C C Chang; Y F Kuo; H C Chiu; J L Lee; T W Wong; S H Jee
Journal:  J Surg Res       Date:  1995-12       Impact factor: 2.192

2.  General immune reactivity in keloid patients.

Authors:  E F Bloch; M G Hall; M J Denson; V Slay-Solomon
Journal:  Plast Reconstr Surg       Date:  1984-03       Impact factor: 4.730

3.  Role of growth factors in scar contraction: an in vitro analysis.

Authors:  S Younai; G Venters; S Vu; L Nichter; M E Nimni; T L Tuan
Journal:  Ann Plast Surg       Date:  1996-05       Impact factor: 1.539

4.  Treatment of earlobe keloids with surgery plus adjuvant intralesional verapamil and pressure earrings.

Authors:  W T Lawrence
Journal:  Ann Plast Surg       Date:  1996-08       Impact factor: 1.539

5.  Co-ordinate induction of collagen type I and biglycan expression in keloids.

Authors:  N Hunzelmann; S Anders; S Sollberg; E Schönherr; T Krieg
Journal:  Br J Dermatol       Date:  1996-09       Impact factor: 9.302

6.  Hyaluronic acid metabolism in keloid fibroblasts.

Authors:  S M Alaish; D R Yager; R F Diegelmann; I K Cohen
Journal:  J Pediatr Surg       Date:  1995-07       Impact factor: 2.545

7.  The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis.

Authors:  D A Bettinger; D R Yager; R F Diegelmann; I K Cohen
Journal:  Plast Reconstr Surg       Date:  1996-10       Impact factor: 4.730

8.  Modulation of collagen synthesis by transforming growth factor-beta in keloid and hypertrophic scar fibroblasts.

Authors:  S Younai; L S Nichter; T Wellisz; J Reinisch; M E Nimni; T L Tuan
Journal:  Ann Plast Surg       Date:  1994-08       Impact factor: 1.539

9.  Laser treatment of scars.

Authors:  M P Goldman; R E Fitzpatrick
Journal:  Dermatol Surg       Date:  1995-08       Impact factor: 3.398

10.  Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts.

Authors:  T L Tuan; J Y Zhu; B Sun; L S Nichter; M E Nimni; W E Laug
Journal:  J Invest Dermatol       Date:  1996-05       Impact factor: 8.551

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  3 in total

1.  LETTER TO THE EDITOR Abnormal Responses of Keloid Tissue to Wounding Identified Using In Vitro Model System.

Authors:  Dorothy M Supp; Kathryn Glaser; Jennifer M Hahn; Kevin L McFarland; Steven T Boyce
Journal:  Eplasty       Date:  2012-04-12

Review 2.  5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Comprehensive Review of the Literature.

Authors:  Vidhi V Shah; Adam S Aldahan; Stephanie Mlacker; Mohammed Alsaidan; Sahal Samarkandy; Keyvan Nouri
Journal:  Dermatol Ther (Heidelb)       Date:  2016-04-22

3.  Can intralesional cryotherapy reshape the management of difficult keloid scars?

Authors:  Charlotte Defty; Jonathan J Cubitt; Maxwell Sc Murison
Journal:  Scars Burn Heal       Date:  2016-12-05
  3 in total

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