Literature DB >> 1929522

No sensory neuropathy during pyridoxine treatment in homocystinuria.

C Mpofu1, S M Alani, C Whitehouse, B Fowler, J E Wraith.   

Abstract

Seventeen patients with cystathionine synthase deficiency homocystinuria were examined clinically and neurophysiologically for evidence of sensory neuropathy. All had received high dose pyridoxine (vitamin B-6) for many years. Absence of neurological disturbance in all cases suggests long term treatment with pyridoxine in the dosages used in homocystinuric patients is not harmful.

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Year:  1991        PMID： 1929522      PMCID： PMC1793039          DOI： 10.1136/adc.66.9.1081

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  5 in total

1.  Plasma pyridoxal-5-phosphate level as risk index for coronary artery disease.

Authors:  W J Serfontein; J B Ubbink; L S De Villiers; C H Rapley; P J Becker
Journal:  Atherosclerosis       Date:  1985-06       Impact factor: 5.162

Review 2.  Safety of pyridoxine--a review of human and animal studies.

Authors:  M Cohen; A Bendich
Journal:  Toxicol Lett       Date:  1986-12       Impact factor: 4.372

3.  Sensory neuropathy with low-dose pyridoxine.

Authors:  G J Parry; D E Bredesen
Journal:  Neurology       Date:  1985-10       Impact factor: 9.910

4.  Plasma content of B6 vitamers and its relationship to hepatic vitamin B6 metabolism.

Authors:  L Lumeng; A Lui; T K Li
Journal:  J Clin Invest       Date:  1980-10       Impact factor: 14.808

5.  Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome.

Authors:  H Schaumburg; J Kaplan; A Windebank; N Vick; S Rasmus; D Pleasure; M J Brown
Journal:  N Engl J Med       Date:  1983-08-25       Impact factor: 91.245
  5 in total
  4 in total

1.  Homocystinuria.

Authors:  D M Isherwood
Journal:  BMJ       Date:  1996-10-26

2.  Sensory neuropathy and vitamin B6 treatment in homocystinuria.

Authors:  A C Ludolph; H Masur; C Oberwittler; H G Koch; K Ullrich
Journal:  Eur J Pediatr       Date:  1993-03       Impact factor: 3.183

Review 3.  Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control.

Authors:  J R Miranda-Massari; M J Gonzalez; F J Jimenez; M Z Allende-Vigo; J Duconge
Journal:  Curr Clin Pharmacol       Date:  2011-11

Review 4.  Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency.

Authors:  Andrew A M Morris; Viktor Kožich; Saikat Santra; Generoso Andria; Tawfeg I M Ben-Omran; Anupam B Chakrapani; Ellen Crushell; Mick J Henderson; Michel Hochuli; Martina Huemer; Miriam C H Janssen; Francois Maillot; Philip D Mayne; Jenny McNulty; Tara M Morrison; Helene Ogier; Siobhan O'Sullivan; Markéta Pavlíková; Isabel Tavares de Almeida; Allyson Terry; Sufin Yap; Henk J Blom; Kimberly A Chapman
Journal:  J Inherit Metab Dis       Date:  2016-10-24       Impact factor: 4.982
  4 in total

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