Literature DB >> 19294961

Evidence of dissociated arousal states during NREM parasomnia from an intracerebral neurophysiological study.

Michele Terzaghi1, Ivana Sartori, Laura Tassi, Giuseppe Didato, Valter Rustioni, Giorgio LoRusso, Raffaele Manni, Lino Nobili.   

Abstract

STUDY
OBJECTIVES: Arousal parasomnias are expressions of sleep/ wake state dissociations in which wakefulness and NREM sleep seem to coexist. We describe the results of a neurophysiological (intracerebral EEG) investigation that captured an episode of confusional arousal.
DESIGN: Observational analysis.
SETTING: Tertiary sleep center. SUBJECT: A 20-year-old male with refractory focal epilepsy. MEASUREMENTS AND
RESULTS: The intracerebral EEG findings documented the presence of a local arousal of the motor and cingulate cortices associated with increased delta activity in the frontoparietal associative cortices; these findings were noted preceding the onset and persisting throughout the episode.
CONCLUSIONS: The presence of dissociated sleep/wake states in confusional arousals is the expression not of a global phenomenon, but rather of the coexistence of different local states of being: arousal of the motor and cingulate cortices and inhibition of the associative ones. Whether this is an exclusive feature of NREM parasomnias, or a common substrate on which other triggering elements act, needs to be clarified.

Entities:  

Mesh:

Year:  2009        PMID: 19294961      PMCID: PMC2647795          DOI: 10.1093/sleep/32.3.409

Source DB:  PubMed          Journal:  Sleep        ISSN: 0161-8105            Impact factor:   5.849


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