Literature DB >> 19294712

Total synthesis of ciguatoxin.

Akinari Hamajima1, Minoru Isobe.   

Abstract

Something fishy: Ciguatoxin (see structure) is one of the principal toxins involved in ciguatera poisoning and the target of a total synthesis involving the coupling of three segments. The key transformations in this synthesis feature acetylene-dicobalthexacarbonyl complexation.

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Year:  2009        PMID： 19294712     DOI： 10.1002/anie.200805996

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  7 in total

Review 1.  The development of endo-selective epoxide-opening cascades in water.

Authors:  Christopher J Morten; Jeffery A Byers; Aaron R Van Dyke; Ivan Vilotijevic; Timothy F Jamison
Journal:  Chem Soc Rev       Date:  2009-09-16       Impact factor: 54.564

Review 2.  Update on methodologies available for ciguatoxin determination: perspectives to confront the onset of ciguatera fish poisoning in Europe.

Authors:  Amandine Caillaud; Pablo de la Iglesia; H Taiana Darius; Serge Pauillac; Katerina Aligizaki; Santiago Fraga; Mireille Chinain; Jorge Diogène
Journal:  Mar Drugs       Date:  2010-06-14       Impact factor: 5.118

3.  TMSOTf mediated stereoselective synthesis of α-C-glycosides from unactivated aryl acetylenes.

Authors:  Heshan Chen; Xiaosheng Luo; Saifeng Qiu; Wengjie Sun; Jianbo Zhang
Journal:  Glycoconj J       Date:  2016-08-26       Impact factor: 2.916

Review 4.  Total synthesis and related studies of large, strained, and bioactive natural products.

Authors:  Masahiro Hirama
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2016       Impact factor: 3.493

5.  Bidirectional Synthesis of the IJK Fragment of Ciguatoxin CTX3C by Sequential Double Ring-Closing Metathesis and Tsuji-Trost Allylation.

Authors:  Michael Popadynec; Helen Gibbard; J Stephen Clark
Journal:  Org Lett       Date:  2020-04-19       Impact factor: 6.005

6.  Stereoselective Synthesis of the I-L Fragment of the Pacific Ciguatoxins.

Authors:  J Stephen Clark; Michael Popadynec
Journal:  Toxins (Basel)       Date:  2020-11-24       Impact factor: 4.546

Review 7.  Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them.

Authors:  Christopher R Loeffler; Luciana Tartaglione; Miriam Friedemann; Astrid Spielmeyer; Oliver Kappenstein; Dorina Bodi
Journal:  Int J Environ Res Public Health       Date:  2021-03-15       Impact factor: 3.390
  7 in total

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