Literature DB >> 19292908

Incidental carcinoma of the prostate gland presenting with initial manifestation of disseminated intravascular coagulopathy (dic) in a middle aged man: a case report.

Ayo Abdulkadir Salako1, Olukayode Adeolu Arowolo, Emmanuel Abidemi Omonisi, Adewale Oluseye Adisa, Nicholas Akinwale Titiloye, Kayode Adelusola.   

Abstract

BACKGROUND: Incidental carcinoma of the prostate gland is a common clinical problem among elderly males but this malignancy presenting initially with features of Disseminated Intravascular Coagulopathy (DIC) in the African blacks is rare. Disseminateded intravascular coagulathy is the most frequent coagulation disorder in patients with prostate cancer, However DIC as a first manifestation of prostate cancer is unusual. CASE REPORT: This paper reports a case of a 56 year old Nigerian civil servant who presented initially with clinical features of DIC characterised by bleeding from multilple orifices but was subsequently diagnosed at autopsy to be infiltrating adenocarcinoma of the prostate.
CONCLUSION: This rare case of DIC should be considered especially in elderly men when no other cause can be found for coagulopathy.

Entities:  

Year:  2009        PMID: 19292908      PMCID: PMC2783100          DOI: 10.1186/1757-1626-2-144

Source DB:  PubMed          Journal:  Cases J        ISSN: 1757-1626


  8 in total

Review 1.  Disseminated intravascular coagulation.

Authors:  M Levi; H Ten Cate
Journal:  N Engl J Med       Date:  1999-08-19       Impact factor: 91.245

2.  Cancer and DIC.

Authors:  M Levi
Journal:  Haemostasis       Date:  2001

Review 3.  Coagulopathy in prostate cancer.

Authors:  C de la Fouchardière; A Flechon; J P Droz
Journal:  Neth J Med       Date:  2003-11       Impact factor: 1.422

4.  Prostatic carcinoma presenting as a haemorrhagic diathesis after dental extraction.

Authors:  J McKechnie
Journal:  Br Dent J       Date:  1989-04-22       Impact factor: 1.626

5.  Subcutaneous bleeding: first sign of prostate cancer.

Authors:  J B Jensen; N C Langkilde
Journal:  Scand J Urol Nephrol       Date:  2000-06

6.  [Prostatic adenocarcinoma revealed by disseminated intravascular coagulation and fibrinolysis].

Authors:  R Rabii; L Salomon; A Hodznek; F Saint; A Cicco; D K Chopin; C C Abbou
Journal:  Ann Urol (Paris)       Date:  2002-07

7.  Coagulopathy in the prostate cancer patient: prevalence and clinical relevance.

Authors:  A S Adamson; J L Francis; R O Witherow; M E Snell
Journal:  Ann R Coll Surg Engl       Date:  1993-03       Impact factor: 1.891

8.  Untreated prostatic carcinoma is not associated with frequent thrombohemorrhagic disorders.

Authors:  B Drewinko; P Cobb; V Guinee; G Giacco; J M Trujillo; A von Eschenbach
Journal:  Urology       Date:  1987-07       Impact factor: 2.649

  8 in total
  4 in total

1.  Disseminated Intravascular Coagulation as the Initial Presentation of Metastatic Prostate Adenocarcinoma.

Authors:  Daniel J Greenberg
Journal:  Cureus       Date:  2021-05-04

2.  Massive Bleeding as the First Clinical Manifestation of Metastatic Prostate Cancer due to Disseminated Intravascular Coagulation with Enhanced Fibrinolysis.

Authors:  Mónica Palma Anselmo; Gustavo Nobre de Jesus; João Madeira Lopes; Rui M M Victorino; João Meneses Santos
Journal:  Case Rep Hematol       Date:  2016-10-10

3.  An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report.

Authors:  Jurij Ales Kosir; Mensur Salihovic; Primoz Sever; Jasna Klen
Journal:  Int J Surg Case Rep       Date:  2020-05-29

Review 4.  An Estimate of the Incidence of Prostate Cancer in Africa: A Systematic Review and Meta-Analysis.

Authors:  Davies Adeloye; Rotimi Adedeji David; Adewale Victor Aderemi; Alexander Iseolorunkanmi; Ayo Oyedokun; Emeka E J Iweala; Nicholas Omoregbe; Charles K Ayo
Journal:  PLoS One       Date:  2016-04-13       Impact factor: 3.240

  4 in total

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