| Literature DB >> 19290501 |
R Pörtner1, C Goepfert, K Wiegandt, R Janssen, E Ilinich, H Paetzold, E Eisenbarth, M Morlock.
Abstract
Technical aspects play an important role in tissue engineering. Especially an improved design of bioreactors is crucial for cultivation of artificial three-dimensional tissues in vitro. Here formation of cartilage-carrier-constructs is used to demonstrate that the quality of the tissue can be significantly improved by using optimized culture conditions (oxygen concentration, growth factor combination) as well as special bioreactor techniques to induce fluid-dynamic, hydrostatic or mechanical load during generation of cartilage.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19290501 DOI： 10.1007/978-3-540-69357-4_7
Source DB: PubMed Journal: Adv Biochem Eng Biotechnol ISSN： 0724-6145 Impact factor: 2.635