Literature DB >> 19287936

[Mortality trend due to accidental tetanus from 1981 to 2004 in Pernambuco and analysis of the impact on intensive care unit attendance].

Pedro Alves da Cruz Gouveia1, Cláudia Elise Ferraz Silva, Demócrito de Barros Miranda Filho, Sylvia Nery Bernardino, Abelardo Gonçalves Escarião, Ricardo Arraes de Alencar Ximenes.   

Abstract

Despite reductions in the incidence of accidental tetanus cases in Brazil, there has not been any significant decrease in its mortality. In this case series, the mortality rates before and after establishing standard management practices for tetanus patients in the intensive care unit at the Oswaldo Cruz University Hospital are compared over the period from 1981 to 2004. Over these 24 years, 1.971 patients were admitted. Before establishing the intensive care unit management, the mortality rate was 35%. The Intensive care unit for attending to tetanus patients was established in 1997. From 1998 to 2004, the mortality rate fell to 12.6%: OR = 0.27 (95% CI = 0.18-0.39); p < 0.001. This trend was seen in all age groups and both sexes. The centralization of attendance for these patients into a single specialized service with early treatment in an intensive care unit has therefore been decisive in reducing the mortality rate. This service can count on the medical team's vast experience of tetanus management, with better treatment of symptoms that forestalls the serious complications from this disease.

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Year:  2009        PMID: 19287936     DOI: 10.1590/s0037-86822009000100011

Source DB:  PubMed          Journal:  Rev Soc Bras Med Trop        ISSN: 0037-8682            Impact factor:   1.581


  2 in total

1.  Seroepidemiology of tetanus in Hangzhou from 2009 to 2018.

Authors:  Yuyang Xu; Yan Liu; Jian Du; Wei Zheng; Shijun Liu; Xuechao Zhang; Xiaoping Zhang; Jun Wang; Xinren Che; Wenwen Gu; Wei Jiang
Journal:  Hum Vaccin Immunother       Date:  2020-05-27       Impact factor: 3.452

2.  Patients with severe accidental tetanus admitted to an intensive care unit in Northeastern Brazil: clinical-epidemiological profile and risk factors for mortality.

Authors:  Marcus Vinícius Dantas da Nóbrega; Ricardo Coelho Reis; Isabel Cristina Veras Aguiar; Timóteo Vasconcelos Queiroz; Ana Claudia Feitosa Lima; Eanes Delgado Barros Pereira; Raquel Feijó de Araújo Ferreira
Journal:  Braz J Infect Dis       Date:  2016-07-29       Impact factor: 3.257

  2 in total

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