Literature DB >> 19281721

Risk factors of recurrent furunculosis.

Abdel-Hady El-Gilany, Hanan Fathy.   

Abstract

This is a case control study of recurrent versus non-recurrent furunculosis. The aim was to identify the risk factors and causative micro-organisms associated with recurrence of furunculosis. Data was collected through an anonymous questionnaire. Weight and height were measured to calculate body mass index and a specimen was drawn from a lesion for culture. A nasal swab was taken to identify nasal Staphylococcus aureus carriers. Staphylococcus aureus was the causative organism in 89 percent and 100 percent of recurrent and non-recurrent furuncles, respectively. No significant difference was detected in resistance to the commonly used antibiotics. Logistic regression analysis revealed that the most important independent predictor of recurrence was a positive family history. The other independent predictors were anemia, previous antibiotic therapy, diabetes mellitus, previous hospitalization, multiplicity of lesions, personal hygiene and associated skin diseases. Nearly all these risk factors are modifiable, preventable, and/or controllable by simple measures such as sound personal hygiene and a balanced diet. Further research is needed to study if the same organism is implicated in recurrent cases and to test the feasibility as well as cost-benefit of prophylactic use of antibiotics. It is not advisable to use antibiotics to clear nasal carrier of S. aureus in our culture with the large number of possible sources of re-infection other than nasal nares.

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Mesh:

Year:  2009        PMID: 19281721

Source DB:  PubMed          Journal:  Dermatol Online J        ISSN: 1087-2108


  5 in total

1.  Association of recurrent furunculosis with Panton-Valentine leukocidin and the genetic background of Staphylococcus aureus.

Authors:  Helena Masiuk; Katarzyna Kopron; Dorothee Grumann; Christiane Goerke; Julia Kolata; Joanna Jursa-Kulesza; Stefania Giedrys-Kalemba; Barbara M Bröker; Silva Holtfreter
Journal:  J Clin Microbiol       Date:  2010-03-03       Impact factor: 5.948

2.  Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus.

Authors:  Pamela S Hair; Charlene G Echague; Reuben D Rohn; Neel K Krishna; Julius O Nyalwidhe; Kenji M Cunnion
Journal:  J Transl Med       Date:  2012-03-05       Impact factor: 5.531

3.  Possible Immunomodulating Effect of Retinol on Cytokines Secretion in Patients with Recurrent Furunculosis.

Authors:  Danuta Nowicka; Ewelina Grywalska; Anna Hymos; Michał Mielnik; Jacek Roliński
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2017-07-20       Impact factor: 4.291

4.  NK and NKT-Like Cells in Patients with Recurrent Furunculosis.

Authors:  Danuta Nowicka; Ewelina Grywalska; Elżbieta Fitas; Michał Mielnik; Jacek Roliński
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2017-12-13       Impact factor: 4.291

Review 5.  Recurrent furunculosis - challenges and management: a review.

Authors:  Kristina Sophie Ibler; Charles B Kromann
Journal:  Clin Cosmet Investig Dermatol       Date:  2014-02-18
  5 in total

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