Literature DB >> 19280619

Total synthesis of hopeahainol A and hopeanol.

K C Nicolaou1, T Robert Wu, Qiang Kang, David Y-K Chen.   

Abstract

Similar, but different: Possessing almost the same but not identical structures, the recently discovered natural products hopeahainol A (1) and hopeanol (2) exhibit important but differing biological properties (see structures). Their first total synthesis has now been achieved through a series of novel cascade reactions and skeletal rearrangements.

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Year:  2009        PMID： 19280619     DOI： 10.1002/anie.200900438

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  18 in total

Review 1.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

2.  Organic chemistry: Triumph for unnatural synthesis.

Authors:  Stéphane Quideau
Journal:  Nature       Date:  2011-06-22       Impact factor: 49.962

Review 3.  Chemistry and Biology of Resveratrol-Derived Natural Products.

Authors:  Mitchell H Keylor; Bryan S Matsuura; Corey R J Stephenson
Journal:  Chem Rev       Date:  2015-04-02       Impact factor: 60.622

4.  Electrochemical Dimerization of Phenylpropenoids and the Surprising Antioxidant Activity of the Resultant Quinone Methide Dimers.

Authors:  Kevin J Romero; Matthew S Galliher; Mark A R Raycroft; Jean-Philippe R Chauvin; Irene Bosque; Derek A Pratt; Corey R J Stephenson
Journal:  Angew Chem Int Ed Engl       Date:  2018-11-26       Impact factor: 15.336

5.  Structural revision and total synthesis of caraphenol B and C.

Authors:  Scott A Snyder; Zachary G Brill
Journal:  Org Lett       Date:  2011-09-26       Impact factor: 6.005

6.  Harnessing quinone methides: total synthesis of (±)-vaticanol A.

Authors:  Tue H Jepsen; Stephen B Thomas; Yunqing Lin; Christos I Stathakis; Irene de Miguel; Scott A Snyder
Journal:  Angew Chem Int Ed Engl       Date:  2014-05-19       Impact factor: 15.336

7.  Palladium-Catalyzed Chemoselective Activation of sp3 vs sp2 C-H Bonds: Oxidative Coupling To Form Quaternary Centers.

Authors:  Gang Hong; Pradip D Nahide; Uday Kumar Neelam; Peter Amadeo; Arjun Vijeta; John M Curto; Charles E Hendrick; Kelsey F VanGelder; Marisa C Kozlowski
Journal:  ACS Catal       Date:  2019-03-08       Impact factor: 13.084

8.  Synthesis of resveratrol tetramers via a stereoconvergent radical equilibrium.

Authors:  Mitchell H Keylor; Bryan S Matsuura; Markus Griesser; Jean-Philippe R Chauvin; Ryan A Harding; Mariia S Kirillova; Xu Zhu; Oliver J Fischer; Derek A Pratt; Corey R J Stephenson
Journal:  Science       Date:  2016-12-09       Impact factor: 47.728

9.  Synthesis of Vitisins A and D Enabled by a Persistent Radical Equilibrium.

Authors:  Kevin J Romero; Mitchell H Keylor; Markus Griesser; Xu Zhu; Ethan J Strobel; Derek A Pratt; Corey R J Stephenson
Journal:  J Am Chem Soc       Date:  2020-03-24       Impact factor: 15.419

10.  Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones.

Authors:  Xiu-Fen Cheng; Yan Li; Yi-Ming Su; Feng Yin; Jian-Yong Wang; Jie Sheng; Harit U Vora; Xi-Sheng Wang; Jin-Quan Yu
Journal:  J Am Chem Soc       Date:  2013-01-14       Impact factor: 15.419
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