Literature DB >> 19280617

Iron-mediated cleavage of C-C bonds in vicinal tricarbonyl compounds in water.

Jasmin Mecinović1, Refaat B Hamed, Christopher J Schofield.   

Abstract

Three of a kind: Vicinal tricarbonyl compounds undergo C-C cleavage mediated by ferric ions (see scheme). The observed cleavage of ninhydrin and dehydroascorbic acid has relevance for amino acid detection and the metabolism of vitamin C.

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Year:  2009        PMID： 19280617     DOI： 10.1002/anie.200806296

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  5 in total

1.  A miniaturized screen for inhibitors of Jumonji histone demethylases.

Authors:  Masaaki Sakurai; Nathan R Rose; Lena Schultz; Amy M Quinn; Ajit Jadhav; Stanley S Ng; Udo Oppermann; Christopher J Schofield; Anton Simeonov
Journal:  Mol Biosyst       Date:  2009-10-08

2.  Thermally accelerated oxidative degradation of quercetin using continuous flow kinetic electrospray-ion trap-time of flight mass spectrometry.

Authors:  Jeremy S Barnes; Frank W Foss; Kevin A Schug
Journal:  J Am Soc Mass Spectrom       Date:  2013-08-10       Impact factor: 3.109

3.  Reducing Agent-Mediated Nonenzymatic Conversion of 2-Oxoglutarate to Succinate: Implications for Oxygenase Assays.

Authors:  Amjad Khan; Christopher J Schofield; Timothy D W Claridge
Journal:  Chembiochem       Date:  2020-08-18       Impact factor: 3.164

4.  Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

Authors:  Hanna Tarhonskaya; Anna M Rydzik; Ivanhoe K H Leung; Nikita D Loik; Mun Chiang Chan; Akane Kawamura; James S O McCullagh; Timothy D W Claridge; Emily Flashman; Christopher J Schofield
Journal:  Nat Commun       Date:  2014-03-05       Impact factor: 14.919

5.  Facile cleavage of C-C bond: conversion of pyrane derivative to 1,3-oxazin derivative.

Authors:  Zhilan Lin; Xueli Zhang; Xinkui You; Yuan Gao
Journal:  Tetrahedron       Date:  2012-05-30       Impact factor: 2.457
  5 in total

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