P M Lang1, L J Rüger, T Abahji, U Hoffmann, A Crispin, D Irnich. 1. Interdisziplinäre Schmerzambulanz, Klinik für Anästhesiologie, Klinikum Innenstadt der Ludwig-Maximilians-Universität, München, Deutschland. philip.lang@med.uni-muenchen.de
Abstract
BACKGROUND: A neuropathic component to chronic ischemic pain in peripheral arterial disease (PAD) has recently been shown using quantitative sensory testing (QST) and pain questionnaires. The aim of this study was to examine correlations between QST and pain questionnaires in patients with chronic ischemic pain. METHODS: A total of 10 patients with severe PAD (Fontaine stages III and IV) without diabetes mellitus answered a questionnaire and were examined with QST. The questionnaire consisted of several validated instruments which were used to examine the intensity of pain, quality of pain and neuropathic pain (VAS, SF-MPQ, S-LANSS, NPSI). RESULTS: The results of the QST confirmed previously published data. Several terms of the SF-MPQ showed a correlation with parameters of the QST, such as Allodynia (QST) which correlated with the term tender (SF-MPQ) (Spearman's correlation coefficient 0.911; p< or =0.001) and the NPSI subscore evoked pain correlated with the QST parameter wind-up ratio (0.683; p=0.042). CONCLUSION: The results suggest that there might be correlations between psychophysical tests (QST) and pain questionnaires. Subjective perceptions of pain might be represented by a certain pattern in the QST. These connections could contribute to further clarify the pathophysiologic mechanisms leading to the perception of pain.
BACKGROUND: A neuropathic component to chronic ischemic pain in peripheral arterial disease (PAD) has recently been shown using quantitative sensory testing (QST) and pain questionnaires. The aim of this study was to examine correlations between QST and pain questionnaires in patients with chronic ischemic pain. METHODS: A total of 10 patients with severe PAD (Fontaine stages III and IV) without diabetes mellitus answered a questionnaire and were examined with QST. The questionnaire consisted of several validated instruments which were used to examine the intensity of pain, quality of pain and neuropathic pain (VAS, SF-MPQ, S-LANSS, NPSI). RESULTS: The results of the QST confirmed previously published data. Several terms of the SF-MPQ showed a correlation with parameters of the QST, such as Allodynia (QST) which correlated with the term tender (SF-MPQ) (Spearman's correlation coefficient 0.911; p< or =0.001) and the NPSI subscore evoked pain correlated with the QST parameter wind-up ratio (0.683; p=0.042). CONCLUSION: The results suggest that there might be correlations between psychophysical tests (QST) and pain questionnaires. Subjective perceptions of pain might be represented by a certain pattern in the QST. These connections could contribute to further clarify the pathophysiologic mechanisms leading to the perception of pain.
Authors: A Vital; C Vital; C Brechenmacher; J M Serise; S Callen; H Nicolau; J Videau Journal: Clin Neuropathol Date: 1986 Sep-Oct Impact factor: 1.368
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Authors: Philip M Lang; Gabriel M Schober; Roman Rolke; Susanne Wagner; Robert Hilge; Martin Offenbächer; Rolf-Detlef Treede; Ulrich Hoffmann; Dominik Irnich Journal: Pain Date: 2006-05-22 Impact factor: 6.961
Authors: W Iris Zhi; Patricia Chen; Alice Kwon; Connie Chen; Steven E Harte; Lauren Piulson; Susan Li; Sujata Patil; Jun J Mao; Ting Bao Journal: Breast Cancer Res Treat Date: 2019-08-27 Impact factor: 4.872