BACKGROUND: As recent chemotherapy regimens for metastatic colorectal cancer become more and more effective in a neoadjuvant setting before liver surgery, a "complete" clinical response is sometimes documented on imaging. Without operation though, metastatic recurrence is likely to commence within 12 months. Surgeons now face the problem to resect non-visualizable and non-palpable lesions. METHODS: Computer-based virtual surgery planning can be used to fuse pre- and postchemotherapy computed tomography data to develop an operative strategy. This information is then intraoperatively transferred to the liver surface using an image-guided stereotactically navigated ultrasound dissector. This enables the surgeon to perform a resection that is otherwise not possible. RESULTS: During operation, detection of the lesion through palpation or ultrasound was impossible. After registering the virtual operation plan into the navigation system, the planned resection was performed without problems. Histopathologic workup showed vital tumor cells in the specimen. CONCLUSION: The new image-guided stereotactic navigation technique combined with virtual surgery planning can solve the surgeon's dilemma and yield a successful operation.
BACKGROUND: As recent chemotherapy regimens for metastatic colorectal cancer become more and more effective in a neoadjuvant setting before liver surgery, a "complete" clinical response is sometimes documented on imaging. Without operation though, metastatic recurrence is likely to commence within 12 months. Surgeons now face the problem to resect non-visualizable and non-palpable lesions. METHODS: Computer-based virtual surgery planning can be used to fuse pre- and postchemotherapy computed tomography data to develop an operative strategy. This information is then intraoperatively transferred to the liver surface using an image-guided stereotactically navigated ultrasound dissector. This enables the surgeon to perform a resection that is otherwise not possible. RESULTS: During operation, detection of the lesion through palpation or ultrasound was impossible. After registering the virtual operation plan into the navigation system, the planned resection was performed without problems. Histopathologic workup showed vital tumor cells in the specimen. CONCLUSION: The new image-guided stereotactic navigation technique combined with virtual surgery planning can solve the surgeon's dilemma and yield a successful operation.
Authors: Steven R Alberts; William L Horvath; William C Sternfeld; Richard M Goldberg; Michelle R Mahoney; Shaker R Dakhil; Ralph Levitt; Kendrith Rowland; Suresh Nair; Daniel J Sargent; John H Donohue Journal: J Clin Oncol Date: 2005-10-17 Impact factor: 44.544
Authors: Bernard Nordlinger; Eric Van Cutsem; Philippe Rougier; Claus-Henning Köhne; Marc Ychou; Alberto Sobrero; Rene Adam; Dag Arvidsson; Alfredo Carrato; Vassilis Georgoulias; Felice Giuliante; Bengt Glimelius; Markus Golling; Thomas Gruenberger; Josep Tabernero; Harpreet Wasan; Graeme Poston Journal: Eur J Cancer Date: 2007-09-04 Impact factor: 9.162
Authors: Christian Hansen; Jan Wieferich; Felix Ritter; Christian Rieder; Heinz-Otto Peitgen Journal: Int J Comput Assist Radiol Surg Date: 2009-06-19 Impact factor: 2.924
Authors: K J Oldhafer; M Peterhans; A Kantas; A Schenk; G Makridis; S Pelzl; K C Wagner; S Weber; G A Stavrou; M Donati Journal: Chirurg Date: 2018-10 Impact factor: 0.955