Literature DB >> 19279172

First insight into genetic diversity of the Mycobacterium tuberculosis complex in Albania obtained by multilocus variable-number tandem-repeat analysis and spoligotyping reveals the presence of beijing multidrug-resistant isolates.

Silva Tafaj1, Jian Zhang, Yolande Hauck, Christine Pourcel, Hasan Hafizi, Grigor Zoraqi, Christophe Sola.   

Abstract

We characterized a set of 100 Mycobacterium tuberculosis complex clinical isolates from tuberculosis (TB) patients in Albania, typing them with a 24-locus variable-number tandem-repeat-spoligotyping scheme. Depending on the cluster definition, 43 to 49 patients were distributed into 15 to 16 clusters which were likely to be epidemiologically linked, indicative of a recent transmission rate of 28 to 34%. This result suggests that TB is under control in Albania. However, two multidrug-resistant (MDR) Beijing genotypes harboring the same S531A mutation on the rpoB gene were also found, suggesting a potential recent transmission of MDR TB. Three brand new genotypes, Albania-1 to Albania-3, are also described.

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Year:  2009        PMID: 19279172      PMCID: PMC2681852          DOI: 10.1128/JCM.02284-08

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  21 in total

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5.  Rapid identification of mycobacteria to the species level by polymerase chain reaction and restriction enzyme analysis.

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6.  Automated high-throughput genotyping for study of global epidemiology of Mycobacterium tuberculosis based on mycobacterial interspersed repetitive units.

Authors:  P Supply; S Lesjean; E Savine; K Kremer; D van Soolingen; C Locht
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8.  Utility of new 24-locus variable-number tandem-repeat typing for discriminating Mycobacterium tuberculosis clinical isolates collected in Bulgaria.

Authors:  Violeta Valcheva; Igor Mokrousov; Olga Narvskaya; Nalin Rastogi; Nadya Markova
Journal:  J Clin Microbiol       Date:  2008-07-09       Impact factor: 5.948

9.  Molecular characterization of Mycobacterium tuberculosis isolates from different regions of Bulgaria.

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10.  High resolution, on-line identification of strains from the Mycobacterium tuberculosis complex based on tandem repeat typing.

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  8 in total

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Journal:  J Clin Microbiol       Date:  2012-07-18       Impact factor: 5.948

2.  Unusual mycobacterial interspersed repetitive-unit alleles in loci 580 and 4348 among Mycobacterium tuberculosis isolates in Albania.

Authors:  Alberto Trovato; Emanuele Borroni; Silva Tafaj; Hasan Hafizi; Daniela Maria Cirillo
Journal:  J Clin Microbiol       Date:  2014-09-24       Impact factor: 5.948

3.  Map the gap: missing children with drug-resistant tuberculosis.

Authors:  C M Yuen; C A Rodriguez; S Keshavjee; M C Becerra
Journal:  Public Health Action       Date:  2015-03-21

4.  Using affinity propagation for identifying subspecies among clonal organisms: lessons from M. tuberculosis.

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Journal:  BMC Bioinformatics       Date:  2011-06-02       Impact factor: 3.169

5.  A model-based Bayesian estimation of the rate of evolution of VNTR loci in Mycobacterium tuberculosis.

Authors:  R Zachariah Aandahl; Josephine F Reyes; Scott A Sisson; Mark M Tanaka
Journal:  PLoS Comput Biol       Date:  2012-06-28       Impact factor: 4.475

6.  A molecular epidemiological and genetic diversity study of tuberculosis in Ibadan, Nnewi and Abuja, Nigeria.

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Journal:  PLoS One       Date:  2012-06-18       Impact factor: 3.240

7.  Molecular epidemiology of tuberculosis in Sicily, Italy: what has changed after a decade?

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Journal:  BMC Infect Dis       Date:  2014-11-19       Impact factor: 3.090

8.  Beijing lineage of MDR Mycobacterium tuberculosis in Bulgaria, 2007-2011.

Authors:  Stefan Panaiotov; Elizabeta Bachiyska; Stanislava Yordanova; Yuliana Atanasova; Nadia Brankova; Viktoria Levterova; Sarah Sengstake; Richard Anthony; Indra Bergval; Christophe Sola; Todor Kantardjiev
Journal:  Emerg Infect Dis       Date:  2014-11       Impact factor: 6.883

  8 in total

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