| Literature DB >> 19279172 |
Silva Tafaj1, Jian Zhang, Yolande Hauck, Christine Pourcel, Hasan Hafizi, Grigor Zoraqi, Christophe Sola.
Abstract
We characterized a set of 100 Mycobacterium tuberculosis complex clinical isolates from tuberculosis (TB) patients in Albania, typing them with a 24-locus variable-number tandem-repeat-spoligotyping scheme. Depending on the cluster definition, 43 to 49 patients were distributed into 15 to 16 clusters which were likely to be epidemiologically linked, indicative of a recent transmission rate of 28 to 34%. This result suggests that TB is under control in Albania. However, two multidrug-resistant (MDR) Beijing genotypes harboring the same S531A mutation on the rpoB gene were also found, suggesting a potential recent transmission of MDR TB. Three brand new genotypes, Albania-1 to Albania-3, are also described.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19279172 PMCID: PMC2681852 DOI: 10.1128/JCM.02284-08
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948