Literature DB >> 19279087

Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications.

Isabelle Barde1, Elisa Laurenti, Sonia Verp, Anna Claire Groner, Christopher Towne, Viviane Padrun, Patrick Aebischer, Andreas Trumpp, Didier Trono.   

Abstract

KAP1 is an essential cofactor of KRAB zinc finger proteins, a family of vertebrate-specific epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and human genomes. So far, KRAB/KAP1-mediated gene regulation has been studied within the environment of chromosomal DNA. Here we demonstrate that KRAB/KAP1 regulation is fully functional within the context of episomal DNA, such as adeno-associated viral and nonintegrated lentiviral vectors, and is correlated with histone modifications typically associated with this epigenetic regulator.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19279087      PMCID： PMC2681943          DOI： 10.1128/JVI.00001-09

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  35 in total

1.  Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

Authors:  V Salucci; A Scarito; L Aurisicchio; S Lamartina; G Nicolaus; S Giampaoli; O Gonzalez-Paz; C Toniatti; H Bujard; W Hillen; G Ciliberto; F Palombo
Journal:  Gene Ther       Date:  2002-11       Impact factor: 5.250

2.  Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina.

Authors:  L H McGee Sanftner; K G Rendahl; D Quiroz; M Coyne; M Ladner; W C Manning; J G Flannery
Journal:  Mol Ther       Date:  2001-05       Impact factor: 11.454

3.  KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution.

Authors:  Camilla Looman; Magnus Abrink; Charlotta Mark; Lars Hellman
Journal:  Mol Biol Evol       Date:  2002-12       Impact factor: 16.240

4.  Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo.

Authors:  H Nakai; S R Yant; T A Storm; S Fuess; L Meuse; M A Kay
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

5.  Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.

Authors:  Angelo Lombardo; Pietro Genovese; Christian M Beausejour; Silvia Colleoni; Ya-Li Lee; Kenneth A Kim; Dale Ando; Fyodor D Urnov; Cesare Galli; Philip D Gregory; Michael C Holmes; Luigi Naldini
Journal:  Nat Biotechnol       Date:  2007-10-28       Impact factor: 54.908

6.  Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.

Authors:  Biljana Georgievska; Deniz Kirik; Anders Björklund
Journal:  Exp Neurol       Date:  2002-10       Impact factor: 5.330

7.  Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice.

Authors:  Chris Towne; Cédric Raoul; Bernard L Schneider; Patrick Aebischer
Journal:  Mol Ther       Date:  2008-04-15       Impact factor: 11.454

8.  Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse.

Authors:  Philipp Weber; Florence Cammas; Christelle Gerard; Daniel Metzger; Pierre Chambon; Régine Losson; Manuel Mark
Journal:  Development       Date:  2002-05       Impact factor: 6.868

9.  A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.

Authors:  Xiajun Li; Mitsuteru Ito; Fen Zhou; Neil Youngson; Xiaopan Zuo; Philip Leder; Anne C Ferguson-Smith
Journal:  Dev Cell       Date:  2008-10       Impact factor: 12.270

10.  Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.

Authors:  Henriette O'Geen; Sharon L Squazzo; Sushma Iyengar; Kim Blahnik; John L Rinn; Howard Y Chang; Roland Green; Peggy J Farnham
Journal:  PLoS Genet       Date:  2007-04-19       Impact factor: 5.917
View more
  17 in total

1.  Gypsy and the birth of the SCAN domain.

Authors:  Ryan O Emerson; James H Thomas
Journal:  J Virol       Date:  2011-08-24       Impact factor: 5.103

2.  The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo.

Authors:  Anna C Groner; Patrick Tschopp; Ludivine Challet; Jens-Erik Dietrich; Sonia Verp; Sandra Offner; Isabelle Barde; Ivan Rodriguez; Takashi Hiiragi; Didier Trono
Journal:  J Biol Chem       Date:  2012-05-17       Impact factor: 5.157

3.  Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency.

Authors:  Rui Sun; Deguang Liang; Yuan Gao; Ke Lan
Journal:  J Virol       Date:  2014-04-16       Impact factor: 5.103

4.  KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification.

Authors:  Carolin Bürck; Andreas Mund; Julia Berscheminski; Lisa Kieweg; Sarah Müncheberg; Thomas Dobner; Sabrina Schreiner
Journal:  J Virol       Date:  2015-11-04       Impact factor: 5.103

5.  De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET.

Authors:  Helen M Rowe; Marc Friedli; Sandra Offner; Sonia Verp; Daniel Mesnard; Julien Marquis; Tugce Aktas; Didier Trono
Journal:  Development       Date:  2013-02-01       Impact factor: 6.868

Review 6.  KAP1 protein: an enigmatic master regulator of the genome.

Authors:  Sushma Iyengar; Peggy J Farnham
Journal:  J Biol Chem       Date:  2011-06-07       Impact factor: 5.157

7.  Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch.

Authors:  Benjamin Rauwel; Suk Min Jang; Marco Cassano; Adamandia Kapopoulou; Isabelle Barde; Didier Trono
Journal:  Elife       Date:  2015-04-07       Impact factor: 8.140

Review 8.  Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family.

Authors:  Gernot Wolf; David Greenberg; Todd S Macfarlan
Journal:  Mob DNA       Date:  2015-10-02

9.  Specific micro RNA-regulated TetR-KRAB transcriptional control of transgene expression in viral vector-transduced cells.

Authors:  Virginie Pichard; Dominique Aubert; Sebastien Boni; Severine Battaglia; Dejana Ivacik; Tuan Huy Nguyen; Patrick Arbuthnot; Nicolas Ferry
Journal:  PLoS One       Date:  2012-12-14       Impact factor: 3.240

10.  Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates.

Authors:  Caroline Le Guiner; Knut Stieger; Alice Toromanoff; Mickaël Guilbaud; Alexandra Mendes-Madeira; Marie Devaux; Lydie Guigand; Yan Cherel; Philippe Moullier; Fabienne Rolling; Oumeya Adjali
Journal:  PLoS One       Date:  2014-09-23       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.