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Literature DB >> 19278597

Effect of excessive salt intake: role of plasma sodium.

Stefan Reuter¹, Eckhart Büssemaker, Martin Hausberg, Hermann Pavenstädt, Uta Hillebrand.

Abstract

Sodium chloride is a normal and necessary constituent of food and the main cause for the rise in arterial pressure that occurs with age. Changes in dietary salt intake can cause changes in plasma sodium. Even a small increase has been shown to be harmful, for example, by increasing left ventricular mass, thickening and narrowing resistance arteries, and stiffening endothelial cells. Therefore, it is possible that an increase in plasma sodium is an important pressor mechanism. This review discusses the role of dietary sodium and plasma sodium, with a special focus on their impact on the endothelial cell.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19278597 DOI： 10.1007/s11906-009-0018-5

Source DB: PubMed Journal: Curr Hypertens Rep ISSN： 1522-6417 Impact factor: 5.369

63 in total

Review 1. Is the vascular endothelium under the control of aldosterone? Facts and hypothesis.

Authors: Hans Oberleithner
Journal: Pflugers Arch Date: 2007-02-07 Impact factor: 3.657

Review 2. Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension.

Authors: Carmine Zoccali
Journal: J Am Soc Nephrol Date: 2006-04 Impact factor: 10.121

Effect of excessive salt intake: role of plasma sodium.

Review 1. Is the vascular endothelium under the control of aldosterone? Facts and hypothesis.

Review 2. Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension.

Review 3. Diet and hypertension: anthropology, epidemiology, and public health implications.

4. Salt and blood pressure: a community trial.

5. Plasma sodium: ignored and underestimated.

6. Angiotensin II, interstitial inflammation, and the pathogenesis of salt-sensitive hypertension.

7. Nephrosclerosis and aortic atherosclerosis from age 6 to 70 years in the United States and Mexico.

Review 8. Sodium chloride, extracellular fluid volume, and blood pressure regulation.

9. Red-cell lithium-sodium countertransport and renal lithium clearance in hypertension.

10. Human endothelium: target for aldosterone.

1. Changes in arterial stiffness following dialysis in relation to overhydration and to endothelial function.

2. Creatine kinase and renal sodium excretion in African and European men on a high sodium diet.

3. NaCl potentiates human fibrocyte differentiation.

4. Small increases in plasma sodium are associated with higher risk of mortality in a healthy population.

5. Classification of different degrees of adiposity in sedentary rats.