Literature DB >> 19277545

Infrared multiphoton dissociation mass spectrometry for structural elucidation of oligosaccharides.

Bensheng Li1, Hyun Joo An, Jerry L Hedrick, Carlito B Lebrilla.   

Abstract

The structural elucidation of oligosaccharides remains a major challenge. Mass spectrometry provides a rapid and convenient method for structural elucidation on the basis of tandem mass spectrometry. Ions are commonly selected and subjected to collision-induced dissociation (CID) to obtain structural information. However, a disadvantage of CID is the decrease in both the degree and efficiency of dissociation with increasing mass. In this chapter, we illustrate the use of infrared multiphoton dissociation (IRMPD) to obtain structural information for O- and N-linked oligosaccharides. The IRMPD and CID behaviors of oligosaccharides are compared.

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Year:  2009        PMID: 19277545     DOI: 10.1007/978-1-59745-022-5_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  7 in total

1.  Structural characterization of neutral oligosaccharides by laser-enhanced in-source decay of MALDI-FTICR MS.

Authors:  Hongmei Yang; Yingning Yu; Fengrui Song; Shuying Liu
Journal:  J Am Soc Mass Spectrom       Date:  2011-03-10       Impact factor: 3.109

Review 2.  Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.

Authors:  David J Harvey
Journal:  Mass Spectrom Rev       Date:  2014-05-26       Impact factor: 10.946

3.  Structure determination by MALDI-IRMPD mass spectrometry and exoglycosidase digestions of O-linked oligosaccharides from Xenopus borealis egg jelly.

Authors:  Bensheng Li; Scott C Russell; Jinhua Zhang; Jerry L Hedrick; Carlito B Lebrilla
Journal:  Glycobiology       Date:  2011-01-09       Impact factor: 4.313

4.  Resolving Heparan Sulfate Oligosaccharide Positional Isomers Using Hydrophilic Interaction Liquid Chromatography-Cyclic Ion Mobility Mass Spectrometry.

Authors:  Gustavo J Cavallero; Joseph Zaia
Journal:  Anal Chem       Date:  2022-01-28       Impact factor: 6.986

5.  Is high throughput glycomics possible?

Authors:  Carlito B Lebrilla
Journal:  Mass Spectrom (Tokyo)       Date:  2013-04-15

Review 6.  Advances in analysis of human milk oligosaccharides.

Authors:  L Renee Ruhaak; Carlito B Lebrilla
Journal:  Adv Nutr       Date:  2012-05-01       Impact factor: 8.701

7.  Identification of structurally closely related monosaccharide and disaccharide isomers by PMP labeling in conjunction with IM-MS/MS.

Authors:  Hongmei Yang; Lei Shi; Xiaoyu Zhuang; Rui Su; Debin Wan; Fengrui Song; Jinying Li; Shuying Liu
Journal:  Sci Rep       Date:  2016-06-16       Impact factor: 4.379

  7 in total

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