Literature DB >> 19276545

Cryptococcal meningitis misdiagnosed as Alzheimer's disease: complete neurological and cognitive recovery with treatment.

Michael Hoffmann1, Juan Muniz, Elizabeth Carroll, Jorge De Villasante.   

Abstract

A sixty-two year old man, with a background of Alzheimer's disease for the past three years, acutely presented with imbalance, headaches, and dizziness. Examination revealed a profound frontal disinhibited and dysexecutive syndrome and brain imaging notable for leptomeningeal enhancement; laboratory data confirmed cryptococcal meningitis. Four months after treatment, the patient was normal neurologically, cognitively and neuroradiologically. The specific cognitive impairment and neuroradiological findings may be clues to differing dementia etiologies.

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Year:  2009        PMID： 19276545     DOI： 10.3233/JAD-2009-0985

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN： 1387-2877            Impact factor:   4.472


  17 in total

1.  Predictors of neurocognitive outcomes on antiretroviral therapy after cryptococcal meningitis: a prospective cohort study.

Authors:  Renee Donahue Carlson; Melissa A Rolfes; Kate E Birkenkamp; Noeline Nakasujja; Radha Rajasingham; David B Meya; David R Boulware
Journal:  Metab Brain Dis       Date:  2014-01-09       Impact factor: 3.584

2.  Assessing the chronic neuropsychologic sequelae of human immunodeficiency virus-negative cryptococcal meningitis by using diffusion tensor imaging.

Authors:  C-H Lu; H-L Chen; W-N Chang; N-W Tsai; H-C Wang; T-M Yang; Y-J Lin; C-P Lin; C-C Chen; B-C Cheng; W-C Lin
Journal:  AJNR Am J Neuroradiol       Date:  2011-05-19       Impact factor: 3.825

3.  Alzheimer's disease and disseminated mycoses.

Authors:  R Alonso; D Pisa; A Rábano; L Carrasco
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-01-23       Impact factor: 3.267

Review 4.  Infectious immunity in the central nervous system and brain function.

Authors:  Robyn S Klein; Charise Garber; Nicole Howard
Journal:  Nat Immunol       Date:  2017-01-16       Impact factor: 25.606

Review 5.  Neuroimaging of rapidly progressive dementias, part 2: prion, inflammatory, neoplastic, and other etiologies.

Authors:  A J Degnan; L M Levy
Journal:  AJNR Am J Neuroradiol       Date:  2013-02-14       Impact factor: 3.825

6.  Evaluation of Patients With Cognitive Impairment Due to Suspected Idiopathic Normal-Pressure Hydrocephalus at Medical Centers for Dementia: A Nationwide Hospital-Based Survey in Japan.

Authors:  Hiroaki Kazui; Mamoru Hashimoto; Shigetoshi Takeda; Yasuji Chiba; Tokiko Goto; Katsuhiro Fuchino
Journal:  Front Neurol       Date:  2022-05-27       Impact factor: 4.086

7.  Alzheimer's disease: a pathogenetic autoimmune disorder caused by herpes simplex in a gene-dependent manner.

Authors:  C J Carter
Journal:  Int J Alzheimers Dis       Date:  2010-12-29

8.  The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease.

Authors:  C J Carter
Journal:  ISRN Neurol       Date:  2011-07-12

9.  Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System.

Authors:  Chris Carter
Journal:  Int J Alzheimers Dis       Date:  2011-12-29

10.  The human frontal lobes and frontal network systems: an evolutionary, clinical, and treatment perspective.

Authors:  Michael Hoffmann
Journal:  ISRN Neurol       Date:  2013-03-14
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