Literature DB >> 19276254

HER-2, notch, and breast cancer stem cells: targeting an axis of evil.

Hasan Korkaya1, Max S Wicha.   

Abstract

Increasing evidence indicates that tumor-initiating (cancer stem) cells may contribute to treatment resistance and relapse, suggesting that improved clinical outcome will require effective targeting of this cell population. Recent studies suggest that the remarkable clinical efficacy of trastuzumab may relate to its ability to target cancer stem cell populations.

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Year:  2009        PMID： 19276254     DOI： 10.1158/1078-0432.CCR-08-3087

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  61 in total

Review 1.  Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition.

Authors:  Stephanie M Tortorella; Simon G Royce; Paul V Licciardi; Tom C Karagiannis
Journal:  Antioxid Redox Signal       Date:  2014-12-19       Impact factor: 8.401

2.  A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer.

Authors:  Benjamin T Spike; Dannielle D Engle; Jennifer C Lin; Samantha K Cheung; Justin La; Geoffrey M Wahl
Journal:  Cell Stem Cell       Date:  2012-02-03       Impact factor: 24.633

Review 3.  The cancer stem cell paradigm: a new understanding of tumor development and treatment.

Authors:  Johnathan D Ebben; Daniel M Treisman; Michael Zorniak; Raman G Kutty; Paul A Clark; John S Kuo
Journal:  Expert Opin Ther Targets       Date:  2010-06       Impact factor: 6.902

Review 4.  Targeting Notch to target cancer stem cells.

Authors:  Antonio Pannuti; Kimberly Foreman; Paola Rizzo; Clodia Osipo; Todd Golde; Barbara Osborne; Lucio Miele
Journal:  Clin Cancer Res       Date:  2010-06-08       Impact factor: 12.531

Review 5.  Targeting breast cancer stem cells.

Authors:  Suling Liu; Max S Wicha
Journal:  J Clin Oncol       Date:  2010-05-24       Impact factor: 44.544

Review 6.  Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells.

Authors:  Shanchun Guo; Mingli Liu; Guangdi Wang; Marta Torroella-Kouri; Ruben R Gonzalez-Perez
Journal:  Biochim Biophys Acta       Date:  2012-01-24

Review 7.  Cancer stem cells and their mechanism of chemo-radiation resistance.

Authors:  Yonghyun Kim; Kyeung Min Joo; Juyoun Jin; Do-Hyun Nam
Journal:  Int J Stem Cells       Date:  2009-05       Impact factor: 2.500

8.  Finally! A model for progesterone receptor action in normal human breast.

Authors:  John P Lydon; Dean P Edwards
Journal:  Endocrinology       Date:  2009-07       Impact factor: 4.736

9.  Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.

Authors:  S Eliasz; S Liang; Y Chen; M A De Marco; O Machek; S Skucha; L Miele; M Bocchetta
Journal:  Oncogene       Date:  2010-02-15       Impact factor: 9.867

10.  Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis.

Authors:  Suruchi Mittal; Deepa Subramanyam; Devaveena Dey; Rekha V Kumar; Annapoorni Rangarajan
Journal:  Mol Cancer       Date:  2009-12-23       Impact factor: 27.401
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