Management of inborn errors of metabolism during pregnancy.

An increasing number of women with inherited metabolic disorders survive, conceive and have children. In order to safeguard the health of the mother and the developing embryo, fetus, and newborn during pregnancy, delivery, and the neonatal period it is necessary to be aware of the range of metabolic disorders, the risks to mothers and children, and appropriate management strategies. The roles of the Paediatrician, Obstetrician and Dietitian in the management of Maternal Hyperphenylalaninaemia and phenylketonuria are reviewed.