Literature DB >> 19274854

Biological changes associated with healthy versus pathological aging: a symposium review.

M N Rajah1, S Bastianetto, K Bromley-Brits, R Cools, M D'Esposito, C L Grady, J Poirier, R Quirion, N Raz, E Rogaeva, W Song, J Pruessner.   

Abstract

The Douglas Mental Health University Institute, in collaboration with the McGill Centre for Studies in Aging, organized a 2-day symposium entitled "Biological Changes Associated with Healthy Versus Pathological Aging" that was held in 13 and 14 December 2007 on the Douglas campus. The symposium involved presentations on current trends in aging and dementia research across several sub-disciplines: genetics, neurochemistry, structural and functional neuroimaging and clinical treatment and rehabilitation. The goal of this symposium was to provide a forum for knowledge-transfer between scientists and clinicians with different specializations in order to promote cross-fertilization of research ideas that would lead to future collaborative neuroscience research in aging and dementia. In this review article, we summarize the presentations made by the 13 international scientists at the symposium and highlight: (i) past research, and future research trends in neuroscience of aging and dementia and (ii) links across levels of analysis that can lead to fruitful transdisciplinary research programs that will advance knowledge about the neurobiological changes associated with healthy aging and dementia.

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Year:  2009        PMID: 19274854      PMCID: PMC2671241          DOI: 10.1016/j.arr.2009.01.003

Source DB:  PubMed          Journal:  Ageing Res Rev        ISSN: 1568-1637            Impact factor:   10.895


  54 in total

1.  A quantitative MR study of the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age.

Authors:  Q Mu; J Xie; Z Wen; Y Weng; Z Shuyun
Journal:  AJNR Am J Neuroradiol       Date:  1999-02       Impact factor: 3.825

2.  The implications of cortical recruitment and brain morphology for individual differences in inhibitory function in aging humans.

Authors:  Stan J Colcombe; Arthur F Kramer; Kirk I Erickson; Paige Scalf
Journal:  Psychol Aging       Date:  2005-09

3.  Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood.

Authors:  Jens C Pruessner; Mark W Baldwin; Katarina Dedovic; Robert Renwick; Najmeh Khalili Mahani; Catherine Lord; Michael Meaney; Sonia Lupien
Journal:  Neuroimage       Date:  2005-07-14       Impact factor: 6.556

4.  Task-related activity in prefrontal cortex and its relation to recognition memory performance in young and old adults.

Authors:  Cheryl L Grady; Anthony R McIntosh; Fergus I M Craik
Journal:  Neuropsychologia       Date:  2005-03-23       Impact factor: 3.139

Review 5.  Dopaminergic modulation of cognitive function-implications for L-DOPA treatment in Parkinson's disease.

Authors:  Roshan Cools
Journal:  Neurosci Biobehav Rev       Date:  2005-06-01       Impact factor: 8.989

6.  Oxidative stress potentiates BACE1 gene expression and Abeta generation.

Authors:  Y Tong; W Zhou; V Fung; M A Christensen; H Qing; X Sun; W Song
Journal:  J Neural Transm (Vienna)       Date:  2004-12-22       Impact factor: 3.575

Review 7.  MRI-based hippocampal volumetrics: data acquisition, normal ranges, and optimal protocol.

Authors:  C R Jack; W H Theodore; M Cook; G McCarthy
Journal:  Magn Reson Imaging       Date:  1995       Impact factor: 2.546

Review 8.  Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory.

Authors:  M Natasha Rajah; Mark D'Esposito
Journal:  Brain       Date:  2005-07-27       Impact factor: 13.501

9.  Age-related reductions in human recognition memory due to impaired encoding.

Authors:  C L Grady; A R McIntosh; B Horwitz; J M Maisog; L G Ungerleider; M J Mentis; P Pietrini; M B Schapiro; J V Haxby
Journal:  Science       Date:  1995-07-14       Impact factor: 47.728

10.  Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.

Authors:  J Poirier; M C Delisle; R Quirion; I Aubert; M Farlow; D Lahiri; S Hui; P Bertrand; J Nalbantoglu; B M Gilfix; S Gauthier
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205

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  3 in total

1.  Differences in dynamic and static functional connectivity between young and elderly healthy adults.

Authors:  Ji Eun Park; Seung Chai Jung; Kyeoung Hwa Ryu; Joo Young Oh; Ho Sung Kim; Choong-Gon Choi; Sang Joon Kim; Woo Hyun Shim
Journal:  Neuroradiology       Date:  2017-07-08       Impact factor: 2.804

2.  Alexithymia and aging: a neuropsychological perspective.

Authors:  Marialuisa Onor; Marianna Trevisiol; Mariangela Spano; Eugenio Aguglia; Sergio Paradiso
Journal:  J Nerv Ment Dis       Date:  2010-12       Impact factor: 2.254

Review 3.  Implication of post-translationally modified SOD1 in pathological aging.

Authors:  Kashfia Shafiq; Nitesh Sanghai; Ying Guo; Jiming Kong
Journal:  Geroscience       Date:  2021-02-19       Impact factor: 7.713

  3 in total

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