Literature DB >> 1927485

Treatment of vestibular disorders.

A Itoh1, E Sakata.   

Abstract

At our department, we generally perform inner ear anesthesia with lidocaine and intratympanic dexamethasone injection for treatment of patients with Menière's disease or labyrinthine vertigo due to circulatory disturbances of the inner ear, having failed other conservative treatments. These treatments were performed in 322 patients who consulted us during the past 7 years, including 136 patients with Menière's disease and 186 patients with labyrinthine vertigo. The criteria for evaluation of the therapeutic effect included the AAOO (1972), the AAO-HNS (1985) and Sakata's (1987) method. Both therapeutic methods were effective not only for the inhibition of vertiginous attacks, but also for the treatment of tinnitus. In the overall evaluation of therapeutic effect, dexamethasone injection was more effective than inner ear anesthesia in cases of Menière's disease whereas inner ear anesthesia was more effective than dexamethasone injection in cases of labyrinthine vertigo. When the three methods of evaluation were compared, the rate of positive effect increased in this order: the AAOO method showed fewer positive effects than the AAO-HNS method, and fewer than or equal to Sakata's method. For example in cases of Menière's disease that are resistant to drug therapy, these two therapeutic methods appear to be worthwhile before attempting surgical treatment for refractory vertigo.

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Year:  1991        PMID: 1927485     DOI: 10.3109/00016489109131486

Source DB:  PubMed          Journal:  Acta Otolaryngol Suppl        ISSN: 0365-5237


  27 in total

1.  Therapy of hearing disorders - conservative procedures.

Authors:  Stefan Plontke
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2005-09-28

2.  [Intratympanic injection therapy for therapy refractory acute hearing loss: A safe option for secondary treatment].

Authors:  G Mühlmeier; S Maier; M Maier; H Maier
Journal:  HNO       Date:  2015-10       Impact factor: 1.284

Review 3.  Local inner-ear drug delivery and pharmacokinetics.

Authors:  Alec N Salt; Stefan K R Plontke
Journal:  Drug Discov Today       Date:  2005-10-01       Impact factor: 7.851

Review 4.  Intratympanic steroid therapy for inner ear diseases, a review of the literature.

Authors:  M J R C Alles; M A der Gaag; R J Stokroos
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-05-25       Impact factor: 2.503

5.  Therapeutic strategies in the treatment of Menière's disease: the Italian experience.

Authors:  Nicola Quaranta; P Picciotti; G Porro; B Sterlicchio; G Danesi; P Petrone; Giacinto Asprella Libonati
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-04-11       Impact factor: 2.503

Review 6.  Menière's disease: pathophysiology and treatment.

Authors:  H Thai-Van; M J Bounaix; B Fraysse
Journal:  Drugs       Date:  2001       Impact factor: 9.546

7.  Intratympanic Steroid Treatment of Bell's Palsy in Patients with Comorbid Disease: A Preliminary Report.

Authors:  Deniz Demir; Sena Genç; Mehmet Güven; Mahmut Sinan Yılmaz; Ahmet Kara; Ünal Erkorkmaz
Journal:  J Int Adv Otol       Date:  2020-04       Impact factor: 1.017

Review 8.  Drug delivery for treatment of inner ear disease: current state of knowledge.

Authors:  Andrew A McCall; Erin E Leary Swan; Jeffrey T Borenstein; William F Sewell; Sharon G Kujawa; Michael J McKenna
Journal:  Ear Hear       Date:  2010-04       Impact factor: 3.570

9.  Localized cell and drug delivery for auditory prostheses.

Authors:  Jeffrey L Hendricks; Jennifer A Chikar; Mark A Crumling; Yehoash Raphael; David C Martin
Journal:  Hear Res       Date:  2008-06-07       Impact factor: 3.208

10.  Intratympanic Therapies for Menière's disease.

Authors:  Matthew W Miller; Yuri Agrawal
Journal:  Curr Otorhinolaryngol Rep       Date:  2014-09-01
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