| Literature DB >> 19274683 |
Sergio Rosselli1, Antonella Maggio, Maurizio Bruno, Vivienne Spadaro, Carmen Formisano, Carlo Irace, Carmen Maffettone, Nicola Mascolo.
Abstract
Two furostanol saponins helleboroside A (1) and helleboroside B (2) were isolated from the methanol extract of Helleborus bocconei Ten. subsp. intermedius (Guss.) Greuter and Burdet, along with the furospirostanol saponin 4 and two ecdysones: ecdysterone (5) and polypodyne B (6). Compound 2 was enzymatically hydrolysed to give product 3. The biological activity of all compounds was tested against rat C6 glioma cells showing a significant cytotoxicity for compounds 3, 4 and 6.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19274683 DOI： 10.1002/ptr.2569
Source DB: PubMed Journal: Phytother Res ISSN： 0951-418X Impact factor: 5.878