Literature DB >> 19273951

Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study.

Dimitrios Christoforidis1, Matthew C Pieh, Robert D Madoff, Anders F Mellgren.   

Abstract

PURPOSE: In this study we compared the outcomes of patients with complex cryptoglandular fistulas treated by endorectal advancement flap or anal fistula plug.
METHODS: We performed a retrospective analysis of patients with transsphincteric anal fistulas treated by endorectal advancement flap or anal fistula plug from January 1996 through April 2007. Patients with noncryptoglandular fistulas or insufficient follow-up were excluded. Results were obtained with a combination of chart reviews, mailed questionnaire, and phone interviews. Success was defined as a closed external opening in absence of symptoms at a minimal follow-up time of six months.
RESULTS: Forty-three patients had an endorectal advancement flap and 37 patients had an anal fistula plug procedure. The two cohorts were comparable for age, gender, smoking status, fistula type, and previous failed treatments. The success rate was 63 percent in the endorectal advancement flap group and 32 percent in the anal fistula plug group (P = 0.008), after a mean follow-up of 56 (range, 6-136) months for endorectal advancement flap and 14 (range, 6-22) months for anal fistula plug.
CONCLUSIONS: The current study indicates that the endorectal advancement flap provides a higher success rate than the anal fistula plug. Randomized trials are needed to further elucidate the efficacy and potential functional benefit of the anal fistula plug in the treatment of complex anal fistulas.

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Year:  2009        PMID: 19273951     DOI: 10.1007/DCR.0b013e31819756ac

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  24 in total

1.  Surgery: Are bioprosthetic plugs for complex anal fistulas effective?

Authors:  Oliver Schwandner
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-08       Impact factor: 46.802

2.  Current management of cryptoglandular fistula-in-ano.

Authors:  Joshua I S Bleier; Husein Moloo
Journal:  World J Gastroenterol       Date:  2011-07-28       Impact factor: 5.742

Review 3.  Complex anal fistula remains a challenge for colorectal surgeon.

Authors:  F Cadeddu; F Salis; G Lisi; I Ciangola; G Milito
Journal:  Int J Colorectal Dis       Date:  2015-01-09       Impact factor: 2.571

Review 4.  Rectal advancement flap for the treatment of complex cryptoglandular anal fistulas: a systematic review and meta-analysis.

Authors:  Zutoia Balciscueta; Natalia Uribe; Izaskun Balciscueta; Juan Carlos Andreu-Ballester; Eduardo García-Granero
Journal:  Int J Colorectal Dis       Date:  2017-02-28       Impact factor: 2.571

Review 5.  The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update.

Authors:  Roberto Cirocchi; Stefano Trastulli; Umberto Morelli; Jacopo Desiderio; Carlo Boselli; Amilcare Parisi; Giuseppe Noya
Journal:  Tech Coloproctol       Date:  2012-12-04       Impact factor: 3.781

6.  Cryptoglandular anal fistulas.

Authors:  Andreas Ommer; Alexander Herold; Eugen Berg; Alois Fürst; Marco Sailer; Thomas Schiedeck
Journal:  Dtsch Arztebl Int       Date:  2011-10-21       Impact factor: 5.594

7.  Early outcomes of fluorescence angiography in the setting of endorectal mucosa advancement flaps.

Authors:  J S Turner; A Okonkwo; A Chase; C E Clark
Journal:  Tech Coloproctol       Date:  2017-12-18       Impact factor: 3.781

8.  Randomized controlled trial of minimally invasive surgery using acellular dermal matrix for complex anorectal fistula.

Authors:  Ma-Mu-Ti-Jiang A ba-bai-ke-re; Hao Wen; Hong-Guo Huang; Hui Chu; Ming Lu; Zhong-Sheng Chang; Er-Ha-Ti Ai; Kai Fan
Journal:  World J Gastroenterol       Date:  2010-07-14       Impact factor: 5.742

9.  Prospective evaluation of a new device for the treatment of anal fistulas.

Authors:  Carlo Ratto; Francesco Litta; Lorenza Donisi; Angelo Parello
Journal:  World J Gastroenterol       Date:  2016-08-14       Impact factor: 5.742

10.  Anal fistula plug vs mucosa advancement flap in complex fistula-in-ano: A meta-analysis.

Authors:  Qiang Leng; Hei-Ying Jin
Journal:  World J Gastrointest Surg       Date:  2012-11-27
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