Literature DB >> 19273685

Molecular mechanisms of macrolide resistance in clinical isolates of Mycoplasma pneumoniae from China.

Deli Xin1, Zuhuang Mi, Xu Han, Ling Qin, Jing Li, Tianli Wei, Xiaogeng Chen, Shaojie Ma, Ancun Hou, Gui Li, Dawei Shi.   

Abstract

Fifty clinical Mycoplasma pneumoniae strains were isolated from 370 children with respiratory tract infections. Four strains were susceptible to macrolides, while the other 46 (92%) were macrolide resistant. The molecular mechanism of resistance was shown to be associated with point mutations in 23S rRNA at positions 2063 and 2064.

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Year:  2009        PMID： 19273685      PMCID： PMC2681523          DOI： 10.1128/AAC.01563-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro.

Authors:  N Okazaki; M Narita; S Yamada; K Izumikawa; M Umetsu; T Kenri; Y Sasaki; Y Arakawa; T Sasaki
Journal:  Microbiol Immunol       Date:  2001       Impact factor: 1.955

2.  [Resistance of Mycoplasma pneumoniae to macrolides antibiotics].

Authors:  De-li Xin; An-cun Hou; Tian-li Wei; Qian Li; Qiu-hong Ma
Journal:  Zhonghua Er Ke Za Zhi       Date:  2005-03

3.  Emergence of macrolide-resistant Mycoplasma pneumoniae with a 23S rRNA gene mutation.

Authors:  Miyuki Morozumi; Keiko Hasegawa; Reiko Kobayashi; Nagako Inoue; Satoshi Iwata; Haruo Kuroki; Naohisa Kawamura; Eiichi Nakayama; Takeshi Tajima; Kouichi Shimizu; Kimiko Ubukata
Journal:  Antimicrob Agents Chemother       Date:  2005-06       Impact factor: 5.191

4.  Characterization and molecular analysis of macrolide-resistant Mycoplasma pneumoniae clinical isolates obtained in Japan.

Authors:  Mayumi Matsuoka; Mitsuo Narita; Norio Okazaki; Hitomi Ohya; Tsutomu Yamazaki; Kazunobu Ouchi; Isao Suzuki; Tomoaki Andoh; Tsuyoshi Kenri; Yuko Sasaki; Atsuko Horino; Miharu Shintani; Yoshichika Arakawa; Tsuguo Sasaki
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

5.  First report of macrolide-resistant strains and description of a novel nucleotide sequence variation in the P1 adhesin gene in Mycoplasma pneumoniae clinical strains isolated in France over 12 years.

Authors:  S Pereyre; A Charron; H Renaudin; C Bébéar; C M Bébéar
Journal:  J Clin Microbiol       Date:  2007-09-19       Impact factor: 5.948

6.  Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis.

Authors:  Bernard J Wolff; W Lanier Thacker; Stephanie B Schwartz; Jonas M Winchell
Journal:  Antimicrob Agents Chemother       Date:  2008-07-21       Impact factor: 5.191
  6 in total
  38 in total

1.  Antibiotic sensitivity of 40 Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant isolates from Beijing, China.

Authors:  Fei Zhao; Min Lv; Xiaoxia Tao; Hui Huang; Binghua Zhang; Zhen Zhang; Jianzhong Zhang
Journal:  Antimicrob Agents Chemother       Date:  2011-11-21       Impact factor: 5.191

2.  Multiclonal origin of macrolide-resistant Mycoplasma pneumoniae isolates as determined by multilocus variable-number tandem-repeat analysis.

Authors:  Yang Liu; Xinye Ye; Hong Zhang; Xiaogang Xu; Minggui Wang
Journal:  J Clin Microbiol       Date:  2012-05-30       Impact factor: 5.948

Review 3.  Mycoplasma pneumoniae from the Respiratory Tract and Beyond.

Authors:  Ken B Waites; Li Xiao; Yang Liu; Mitchell F Balish; T Prescott Atkinson
Journal:  Clin Microbiol Rev       Date:  2017-07       Impact factor: 26.132

4.  Genetic diversity and macrolide resistance of Mycoplasma pneumoniae isolates from two consecutive epidemics in Slovenia.

Authors:  R Kogoj; M Praprotnik; T Mrvič; M Korva; D Keše
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-09-26       Impact factor: 3.267

5.  Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children.

Authors:  Li-Shen Shan; Xin Liu; Xin-Yuan Kang; Fei Wang; Xiao-Hua Han; Yun-Xiao Shang
Journal:  World J Pediatr       Date:  2017-01-27       Impact factor: 2.764

6.  Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China.

Authors:  Zibo Zhou; Xiangzhi Li; Xiaojian Chen; Fangjun Luo; Changwang Pan; Xiaoping Zheng; Feng Tan
Journal:  Antimicrob Agents Chemother       Date:  2014-12-01       Impact factor: 5.191

7.  Treatment options in type-2 low asthma.

Authors:  Timothy S C Hinks; Stewart J Levine; Guy G Brusselle
Journal:  Eur Respir J       Date:  2021-01-21       Impact factor: 16.671

Review 8.  Resistance to Macrolide Antibiotics in Public Health Pathogens.

Authors:  Corey Fyfe; Trudy H Grossman; Kathy Kerstein; Joyce Sutcliffe
Journal:  Cold Spring Harb Perspect Med       Date:  2016-10-03       Impact factor: 6.915

9.  Differences in the frequency of 23S rRNA gene mutations in Mycoplasma pneumoniae between children and adults with community-acquired pneumonia: clinical impact of mutations conferring macrolide resistance.

Authors:  Soo Jin Yoo; Hyo-Bin Kim; Sang-Ho Choi; Sang-Oh Lee; Sung-Han Kim; Sang-Bum Hong; Heungsup Sung; Mi-Na Kim
Journal:  Antimicrob Agents Chemother       Date:  2012-09-24       Impact factor: 5.191

10.  Three familial cases of drug-resistant Mycoplasma pneumoniae infection.

Authors:  Shintaro Kamizono; Hitomi Ohya; Sadanobu Higuchi; Norio Okazaki; Mitsuo Narita
Journal:  Eur J Pediatr       Date:  2009-11-08       Impact factor: 3.183
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