Literature DB >> 19272592

FactorY, a bioinformatic resource for genome-wide promoter analysis.

Elizabeth Guruceaga1, Victor Segura, Fernando J Corrales, Angel Rubio.   

Abstract

The interpretation of the complex molecular descriptions generated by high-throughput gene expression technologies is still challenging. The development of new tools to identify common regulatory mechanisms involved in the control of the expression of a set of co-expressed genes, might enhance our capacity to extract functional information from genomic data sets. Here we present FactorY, a website that allows identification of enriched transcription factor binding sites (TFBSs) in the proximal promoter of a cluster of genes, as well as functional interpretation, and intuitive visualization of the results.

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Year:  2009        PMID: 19272592     DOI: 10.1016/j.compbiomed.2009.01.008

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN: 0010-4825            Impact factor:   4.589


  5 in total

1.  Molecular characterization of the Ggamma-globin-Tag transgenic mouse model of hormone refractory prostate cancer: comparison to human prostate cancer.

Authors:  Alfonso Calvo; Carlos Perez-Stable; Victor Segura; Raúl Catena; Elizabeth Guruceaga; Paul Nguewa; David Blanco; Luis Parada; Teresita Reiner; Jeffrey E Green
Journal:  Prostate       Date:  2010-05-01       Impact factor: 4.104

2.  Developmental control of the Nlrp6 inflammasome and a substrate, IL-18, in mammalian intestine.

Authors:  Sarah L Kempster; Gusztav Belteki; Alison J Forhead; Abigail L Fowden; Robert D Catalano; Brian Y Lam; Ian McFarlane; D Stephen Charnock-Jones; Gordon C S Smith
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-11-18       Impact factor: 4.052

3.  GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information.

Authors:  Ruben Nogales-Cadenas; Pedro Carmona-Saez; Miguel Vazquez; Cesar Vicente; Xiaoyuan Yang; Francisco Tirado; Jose María Carazo; Alberto Pascual-Montano
Journal:  Nucleic Acids Res       Date:  2009-05-22       Impact factor: 16.971

4.  Adenovirus VA RNA-derived miRNAs target cellular genes involved in cell growth, gene expression and DNA repair.

Authors:  Oscar Aparicio; Elena Carnero; Xabier Abad; Nerea Razquin; Elizabeth Guruceaga; Victor Segura; Puri Fortes
Journal:  Nucleic Acids Res       Date:  2009-11-19       Impact factor: 16.971

5.  GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases.

Authors:  Sipko van Dam; Rui Cordeiro; Thomas Craig; Jesse van Dam; Shona H Wood; João Pedro de Magalhães
Journal:  BMC Genomics       Date:  2012-10-06       Impact factor: 3.969

  5 in total

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