Fine needle aspiration cytodiagnosis of epidermoid cysts of the spleen. Report of two cases.

Fine needle aspirates of incidentally observed splenic cysts in two young women showed large numbers of squamous cells with pyknotic nuclei but no atypia, resulting in cytodiagnosis of epidermoid cysts of the spleen. This was confirmed in one case by immunocytochemical staining and histologic examination. The origin and differential diagnosis of epidermoid cysts of the spleen are briefly discussed.