OBJECTIVE: This study aims to compare the prevalence of obsessive-compulsive spectrum disorders (OCSD) in psychiatric outpatients with and without a history of rheumatic fever (RF). METHODS: An analytical cross-sectional study assessing a large sample of consecutive psychiatric outpatients at a Brazilian private practice was conducted during a 10-year period. Psychiatric diagnoses were made by a senior psychiatrist based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Best-estimate diagnosis procedure was also performed. RESULTS: The total sample comprised 678 subjects, 13 of whom (1.92%) presented with a previous history of RF. This group showed a higher prevalence of subclinical obsessive-compulsive disorder (P=.025) and OCSD (P=.007) when compared to individuals with no such history. CONCLUSIONS: A previous history of RF was associated with OCSD. These results suggest that clinicians should be encouraged to actively investigate obsessive-compulsive symptoms and related disorders in patients with a positive history of RF.
OBJECTIVE: This study aims to compare the prevalence of obsessive-compulsive spectrum disorders (OCSD) in psychiatric outpatients with and without a history of rheumatic fever (RF). METHODS: An analytical cross-sectional study assessing a large sample of consecutive psychiatric outpatients at a Brazilian private practice was conducted during a 10-year period. Psychiatric diagnoses were made by a senior psychiatrist based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Best-estimate diagnosis procedure was also performed. RESULTS: The total sample comprised 678 subjects, 13 of whom (1.92%) presented with a previous history of RF. This group showed a higher prevalence of subclinical obsessive-compulsive disorder (P=.025) and OCSD (P=.007) when compared to individuals with no such history. CONCLUSIONS: A previous history of RF was associated with OCSD. These results suggest that clinicians should be encouraged to actively investigate obsessive-compulsive symptoms and related disorders in patients with a positive history of RF.
Authors: D Mataix-Cols; E Frans; A Pérez-Vigil; R Kuja-Halkola; C Gromark; K Isomura; L Fernández de la Cruz; E Serlachius; J F Leckman; J J Crowley; C Rück; C Almqvist; P Lichtenstein; H Larsson Journal: Mol Psychiatry Date: 2017-11-14 Impact factor: 15.992
Authors: Dennis L Murphy; Kiara R Timpano; Michael G Wheaton; Benjamin D Greenberg; Euripedes C Miguel Journal: Dialogues Clin Neurosci Date: 2010 Impact factor: 5.986
Authors: Luiz Paulo Bastos Vasconcelos; Marcelle Cristina da Silva Bastos Vasconcelos; Francisco Biagio Murta E Di Flora; Flávio Augusto Paes de Oliveira; Pedro Drummond Lima; Lucas Campos Barbosa E Silva; Breno Camargos Mucelli Spolaor; José Luiz Padilha da Silva; William Antônio de Magalhães Esteves; Maria Carmo P Nunes; Antônio Lúcio Teixeira Journal: Glob Heart Date: 2022-08-29