Literature DB >> 19268785

Leg ulcer treatment.

Philip D Coleridge-Smith1.   

Abstract

Venous ulcers continue to cause problems for patients and health care systems. These are painful and unpleasant for the patient and expensive for health care providers to treat. This brief review highlights effective methods of management. There is level 1 evidence of the efficacy of compression (bandaging or stockings) in healing ulcers as well as maintaining healing. Patients with superficial saphenous reflux, with or without perforating and deep vein incompetence, benefit from superficial venous surgery. This does not speed ulcer healing but is effective at preventing recurrence after healing with compression. Minimally invasive methods of managing incompetence of superficial saphenous trunks, including endovenous laser ablation, radiofrequency ablation, and foam sclerotherapy are probably also effective in treating patients with venous leg ulcers. Perforating vein ligation is commonly combined with superficial venous surgery for leg ulcer patients, but no systematic data are available to define the role of this treatment. Some centers use deep vein reconstruction to restore competence to deep vein valves. Insufficient data have been published to allow any general recommendation to be made for this treatment. A limited number of drugs have efficacy in promoting leg ulcer healing. They may be used in combination with compression treatment in patients with ulcers refractory to other methods of management. No particular ulcer dressing has been shown to be effective in speeding ulcer healing.

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Year:  2009        PMID: 19268785     DOI: 10.1016/j.jvs.2009.01.003

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  2 in total

1.  Development of Glycerol-Rose Bengal-Polidocanol (GRP) foam for enhanced sclerosis of a cyst for cystic diseases.

Authors:  Soohyun Jeong; Sujin Kim; Youngjoo Choi; Han Na Jung; Kangwon Lee; Min Hee Park
Journal:  PLoS One       Date:  2021-01-05       Impact factor: 3.240

2.  Effects of purified Saccharomyces cerevisiae (1→3)-β-glucan on venous ulcer healing.

Authors:  Sarah Dantas Viana Medeiros; Sara Lima Cordeiro; Jéssica Escorel Chaves Cavalcanti; Karina Mendes Melchuna; Aleida Maria da Silva Lima; Irami Araújo Filho; Aldo Cunha Medeiros; Keyla Borges Ferreira Rocha; Elizabeth Maia Oliveira; Eduardo Dantas Baptista Faria; Guilherme Lanzi Sassaki; Hugo Alexandre Oliveira Rocha; Valéria Soraya Farias Sales
Journal:  Int J Mol Sci       Date:  2012-07-02       Impact factor: 6.208

  2 in total

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