| Literature DB >> 19268586 |
Khurshid A Bhat1, Bhahwal A Shah, Kuldeep K Gupta, Anjali Pandey, Sarang Bani, Subhash C Taneja.
Abstract
Semi-synthetic analogs of pinitol were subjected to screening by determining TNF-alpha expression in human neutrophils using flowcytometry. Among the tested compounds, three derivatives displayed more than 50% inhibition of TNF-alpha cytokine secretion in LPS induced stimulated neutrophils and can be considered as potent anti-inflammatory moieties.Entities:
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Year: 2009 PMID： 19268586 DOI： 10.1016/j.bmcl.2009.02.050
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823