| Literature DB >> 19267180 |
Somik Chatterjee1, Jason W Wang, Mary J Cismowski, John R Bower, Kenneth Steven Rosenthal.
Abstract
The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.Entities:
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Year: 2009 PMID： 19267180 DOI： 10.1007/s00705-009-0341-9
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574