Literature DB >> 19265800

Polyethylene glycol-based bidentate ligands to enhance quantum dot and gold nanoparticle stability in biological media.

Bing C Mei1, Kimihiro Susumu, Igor L Medintz, Hedi Mattoussi.   

Abstract

We describe a simple and versatile scheme to prepare a series of poly(ethylene glycol)-based bidentate ligands that permit strong interactions with colloidal semiconductor nanocrystals (quantum dots, QDs) and gold nanoparticles (AuNPs) alike and promote their dispersion in aqueous solutions. These ligands are synthesized by coupling poly(ethylene glycol)s of various chain length to thioctic acid, followed by ring opening of the 1,2-dithiolane moiety to create a bidentate thiol anchoring group with enhanced affinity for CdSe-ZnS core-shell QDs. These ligands provide a straightforward means of preparing QDs and AuNPs that exhibit greater resistance to environmental changes, facilitating their effective use in bioassays and live cell imaging.

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Year:  2009        PMID： 19265800     DOI： 10.1038/nprot.2008.243

Source DB:  PubMed          Journal:  Nat Protoc        ISSN： 1750-2799            Impact factor:   13.491


  30 in total

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Authors:  Z A Peng; X Peng
Journal:  J Am Chem Soc       Date:  2001-01-10       Impact factor: 15.419

2.  Long-term multiple color imaging of live cells using quantum dot bioconjugates.

Authors:  Jyoti K Jaiswal; Hedi Mattoussi; J Matthew Mauro; Sanford M Simon
Journal:  Nat Biotechnol       Date:  2002-12-02       Impact factor: 54.908

3.  Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping.

Authors:  Sungjee Kim; Yong Taik Lim; Edward G Soltesz; Alec M De Grand; Jaihyoung Lee; Akira Nakayama; J Anthony Parker; Tomislav Mihaljevic; Rita G Laurence; Delphine M Dor; Lawrence H Cohn; Moungi G Bawendi; John V Frangioni
Journal:  Nat Biotechnol       Date:  2003-12-07       Impact factor: 54.908

4.  Synthesis of compact multidentate ligands to prepare stable hydrophilic quantum dot fluorophores.

Authors:  H Tetsuo Uyeda; Igor L Medintz; Jyoti K Jaiswal; Sanford M Simon; Hedi Mattoussi
Journal:  J Am Chem Soc       Date:  2005-03-23       Impact factor: 15.419

5.  Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates.

Authors:  Igor L Medintz; Aaron R Clapp; Florence M Brunel; Theresa Tiefenbrunn; H Tetsuo Uyeda; Eddie L Chang; Jeffrey R Deschamps; Philip E Dawson; Hedi Mattoussi
Journal:  Nat Mater       Date:  2006-06-25       Impact factor: 43.841

6.  Quantum dot bioconjugates for ultrasensitive nonisotopic detection.

Authors:  W C Chan; S Nie
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7.  Nearly monodisperse and shape-controlled CdSe nanocrystals via alternative routes: nucleation and growth.

Authors:  Z Adam Peng; Xiaogang Peng
Journal:  J Am Chem Soc       Date:  2002-04-03       Impact factor: 15.419

8.  Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays.

Authors:  Daniele Gerion; Fanqing Chen; Balaji Kannan; Aihua Fu; Wolfgang J Parak; David J Chen; Arunava Majumdar; A Paul Alivisatos
Journal:  Anal Chem       Date:  2003-09-15       Impact factor: 6.986

9.  Self-assembled nanoscale biosensors based on quantum dot FRET donors.

Authors:  Igor L Medintz; Aaron R Clapp; Hedi Mattoussi; Ellen R Goldman; Brent Fisher; J Matthew Mauro
Journal:  Nat Mater       Date:  2003-08-24       Impact factor: 43.841

10.  Sorting fluorescent nanocrystals with DNA.

Authors:  Daniele Gerion; Wolfgang J Parak; Shara C Williams; Daniela Zanchet; Christine M Micheel; A Paul Alivisatos
Journal:  J Am Chem Soc       Date:  2002-06-19       Impact factor: 15.419
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  30 in total

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Authors:  Amanda M Schrand; John J Schlager; Liming Dai; Saber M Hussain
Journal:  Nat Protoc       Date:  2010-03-25       Impact factor: 13.491

2.  Silica-polymer dual layer-encapsulated quantum dots with remarkable stability.

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3.  Synthesis of functionalized amphiphilic polymers for coating quantum dots.

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Journal:  Nat Protoc       Date:  2011-09-15       Impact factor: 13.491

4.  Organic-to-Aqueous Phase Transfer of Cadmium Chalcogenide Quantum Dots using a Sulfur-Free Ligand for Enhanced Photoluminescence and Oxidative Stability.

Authors:  Raul Calzada; Christopher M Thompson; Dana E Westmoreland; Kedy Edme; Emily A Weiss
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5.  The role of ligand coordination on the cytotoxicity of cationic quantum dots in HeLa cells.

Authors:  Yi-Cheun Yeh; Krishnendu Saha; Bo Yan; Oscar R Miranda; Xi Yu; Vincent M Rotello
Journal:  Nanoscale       Date:  2013-12-21       Impact factor: 7.790

6.  Preparation of compact biocompatible quantum dots using multicoordinating molecular-scale ligands based on a zwitterionic hydrophilic motif and lipoic acid anchors.

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Journal:  Nat Protoc       Date:  2015-05-14       Impact factor: 13.491

Review 7.  Luminescent Nanomaterials (I).

Authors:  Hyejin Chang; Michael M Murata; Won-Yeop Rho; Jaehi Kim; Jong Hun Lee; Sang Hun Lee; Dae Hong Jeong; Bong-Hyun Jun
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

8.  Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

Authors:  Okhil K Nag; Michael H Stewart; Jeffrey R Deschamps; Kimihiro Susumu; Eunkeu Oh; Vassiliy Tsytsarev; Qinggong Tang; Alexander L Efros; Roman Vaxenburg; Bryan J Black; YungChia Chen; Thomas J O'Shaughnessy; Stella H North; Lauren D Field; Philip E Dawson; Joseph J Pancrazio; Igor L Medintz; Yu Chen; Reha S Erzurumlu; Alan L Huston; James B Delehanty
Journal:  ACS Nano       Date:  2017-05-30       Impact factor: 15.881

9.  Tension sensing nanoparticles for mechano-imaging at the living/nonliving interface.

Authors:  Yang Liu; Kevin Yehl; Yoshie Narui; Khalid Salaita
Journal:  J Am Chem Soc       Date:  2013-03-26       Impact factor: 15.419

10.  Engineered biocompatible nanoparticles for in vivo imaging applications.

Authors:  Shu Chen; Lijun Wang; Suzanne L Duce; Stuart Brown; Stephen Lee; Andreas Melzer; Alfred Cuschieri; Pascal André
Journal:  J Am Chem Soc       Date:  2010-10-27       Impact factor: 15.419
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