Literature DB >> 19265652

The side story of stem-like glioma cells.

Anders I Persson1, William A Weiss.   

Abstract

In this issue of Cell Stem Stell, Bleau et al. report that activity of the drug transporter ABCG2 defines a tumorigenic stem-like side population (SP) isolated from glioma. Surprisingly, temozolomide, the first-line chemotherapeutic used for treatment of glioma, increased this side population, and even more so when PTEN was deleted.

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Year:  2009        PMID： 19265652     DOI： 10.1016/j.stem.2009.02.004

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  3 in total

1.  Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas.

Authors:  Teodoro Pulvirenti; Maartje Van Der Heijden; Leif A Droms; Jason T Huse; Viviane Tabar; Alan Hall
Journal:  Cancer Res       Date:  2011-10-11       Impact factor: 12.701

2.  Targeting A20 decreases glioma stem cell survival and tumor growth.

Authors:  Anita B Hjelmeland; Qiulian Wu; Sarah Wickman; Christine Eyler; John Heddleston; Qing Shi; Justin D Lathia; Jennifer Macswords; Jeongwu Lee; Roger E McLendon; Jeremy N Rich
Journal:  PLoS Biol       Date:  2010-02-23       Impact factor: 8.029

3.  Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells.

Authors:  V Martín; A M Sanchez-Sanchez; F Herrera; C Gomez-Manzano; J Fueyo; M A Alvarez-Vega; I Antolín; C Rodriguez
Journal:  Br J Cancer       Date:  2013-04-30       Impact factor: 7.640
  3 in total

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