| Literature DB >> 19264294 |
Kaushik Ghosh1, Krishnendu Chandra, Arnab K Ojha, Siddik Sarkar, Syed S Islam.
Abstract
A water-soluble polysaccharide, isolated from fruiting bodies of Lagenaria siceraria, is composed of methyl-alpha-d-galacturonate, 3-O-acetyl methyl-alpha-d-galacturonate, and beta-d-galactose in a ratio of nearly 1:1:1. Compositional analysis, methylation analysis, periodate oxidation, and NMR studies ((1)H, (13)C, 2D-COSY, TOCSY, NOESY, HMQC, and HMBC) revealed the presence of the following repeating unit in the polysaccharide: [carbohydrate structure: see text] This polysaccharide showed cytotoxic activity in vitro against human breast adenocarcinoma cell line (MCF-7).Entities:
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Year: 2009 PMID： 19264294 DOI： 10.1016/j.carres.2009.01.012
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104