OBJECTIVE: The aim of this study was to explore the separate effects of myelomeningocele (MMC) and hydrocephalus on intelligence and neuropsychological functions in a population-based series of children. MATERIAL AND METHODS: Of the 69 children with MMC born in 1992-1999 in western Sweden, nine did not develop hydrocephalus. Eight of them participated in this study and were compared with age- and gender-matched children with MMC in combination with hydrocephalus and with controls. RESULTS: Children with only MMC had an IQ of 103 compared with 75 in those with hydrocephalus added to the MMC and they had significantly better immediate and long-term memory and executive functions. When compared with controls, they had difficulty with learning and executive functions, but when the two children with an IQ of <70 were excluded, those with only MMC performed just as well as the controls. CONCLUSION: Hydrocephalus rather than MMC in itself appeared to cause the cognitive deficits found in children with MMC.
OBJECTIVE: The aim of this study was to explore the separate effects of myelomeningocele (MMC) and hydrocephalus on intelligence and neuropsychological functions in a population-based series of children. MATERIAL AND METHODS: Of the 69 children with MMC born in 1992-1999 in western Sweden, nine did not develop hydrocephalus. Eight of them participated in this study and were compared with age- and gender-matched children with MMC in combination with hydrocephalus and with controls. RESULTS:Children with only MMC had an IQ of 103 compared with 75 in those with hydrocephalus added to the MMC and they had significantly better immediate and long-term memory and executive functions. When compared with controls, they had difficulty with learning and executive functions, but when the two children with an IQ of <70 were excluded, those with only MMC performed just as well as the controls. CONCLUSION:Hydrocephalus rather than MMC in itself appeared to cause the cognitive deficits found in children with MMC.
Authors: Maureen Dennis; Kim Edelstein; Jon Frederick; Kim Copeland; David Francis; Susan E Blaser; Larry A Kramer; James M Drake; Michael Brandt; Ross Hetherington; Jack M Fletcher Journal: Neuropsychologia Date: 2005 Impact factor: 3.139
Authors: M A Scott; J M Fletcher; B L Brookshire; K C Davidson; S H Landry; T C Bohan; L A Kramer; M E Brandt; D J Francis Journal: Neuropsychology Date: 1998-10 Impact factor: 3.295
Authors: Zehra S Hepp; Verena M Haas; Beatrice Latal; Martin Meuli; Ueli Möhrlen; Sonja M Schauer; Robert Steinfeld; Beth A Padden; David A Wille Journal: Dev Med Child Neurol Date: 2021-07-23 Impact factor: 5.449