Literature DB >> 19262593

Fatal Epstein-Barr virus encephalitis in a 12-year-old child: an underappreciated neurological complication?

Ariane Biebl1, Christine Webersinke, Bernadette Traxler, Brigitte Povysil, Dieter Furthner, Klaus Schmitt, Serge Weis.   

Abstract

BACKGROUND: A 12-year-old boy presented to a community hospital with fever, malaise and fatigue. A polymerase chain reaction test of the cerebrospinal fluid was positive for Epstein-Barr virus. Despite intensive care treatment and antiviral drugs, the patient died 1 month after his initial presentation. INVESTIGATIONS: Physical examination, polymerase chain reaction analysis of the cerebrospinal fluid, brain MRI, immunohistochemistry and molecular biological investigations of postmortem brain samples. DIAGNOSIS: Epstein-Barr Virus encephalitis. MANAGEMENT: Aciclovir, intensive care treatment with intubation, sedation, antiepileptic drugs.

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Year:  2009        PMID: 19262593     DOI: 10.1038/ncpneuro1043

Source DB:  PubMed          Journal:  Nat Clin Pract Neurol        ISSN: 1745-834X


  12 in total

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Authors:  Hirotake Hino; Masashi Kamikawa; Teruyuki Hirano; Makoto Uchino
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10.  Virological and immunological characteristics of fatal Epstein-Barr virus mononucleosis in a 17-year-old Caucasian male presenting with meningoencephalitis and hemophagocytic syndrome.

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  2 in total

1.  Expanding the spectrum of neurological disease associated with Epstein-Barr virus activity.

Authors:  M Kleines; J Schiefer; A Stienen; M Blaum; K Ritter; M Häusler
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-05-15       Impact factor: 3.267

2.  Unusual MRI findings in an immunocompetent patient with EBV encephalitis: a case report.

Authors:  Paola Di Carlo; Marcello Trizzino; Lucina Titone; Giuseppina Capra; Piero Colletti; Giovanni Mazzola; Daniela Pistoia; Caterina Sarno
Journal:  BMC Med Imaging       Date:  2011-03-24       Impact factor: 1.930

  2 in total

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