Literature DB >> 19262247

Congenital epulis in the newborn, review of the literature and a case report.

Fatemeh Eghbalian1, Alireza Monsef.   

Abstract

Congenital epulis (CE) is a rare tumor of the newborn, also known as granular cell tumor or congenital gingival granular cell tumor because of its histologic features. Neumann first described CE in 1871. Epulis is seen only in the newborn and is a different entity from other granular cell tumors. CE has a female predilection with 8:1 ratio. Epulis is most frequently located on the anterior maxillary alveolar ridge and usually occurs as a single mass although 10% cases occur as multiple. CE clinically appears as a pedunculated protuberant mass, which may interfere with respiration or feeding. In cases with large lesions mechanical oral and nasal obstruction can impair fetal deglutition and neonatal respiratory efforts resulting in polyhydramnios prenatally or respiratory impairment postnatally. The exact histiogenesis is still uncertain. The recommended treatment is prompt surgical resection. Recurrences of the tumor and damage to future dentition have not been reported. Spontaneous regression of congenital epulis has been reported in a few cases. However, surgical excision is generally indicated due to interference with feeding or respiration. We report a female neonate with congenital multiple tumors in the anterior maxillary alveolar ridge and review the relevant literature. The tumors were resected by surgical excision. The intraoperative and postoperative course was uneventful. Follow-up for 6 months did not show recurrence.

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Year:  2009        PMID: 19262247     DOI: 10.1097/MPH.0b013e31818ab2f7

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  7 in total

1.  A premature newborn with intraoral tumor.

Authors:  Özge Sürmeli-Onay; Arman Api
Journal:  Turk Pediatri Ars       Date:  2014-12-01

2.  EXIT procedure in a neonate with a prenatally diagnosed granular cell tumor.

Authors:  Steffi Mayer; Holger Till; Holger Stepan
Journal:  Pediatr Surg Int       Date:  2010-08-03       Impact factor: 1.827

3.  Extra-tongue oral granular cell tumor: Histological and immunohistochemical aspect.

Authors:  P-L Tobouti; F-M Pigatti; M-C Martins-Mussi; B-T Sedassari; S-C Orsini-Machado de Sousa
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2017-01-01

4.  Congenital Granular Cell Tumor: Case Report and Review.

Authors:  Preston Gardner; Arlene Rozzelle
Journal:  Case Rep Pediatr       Date:  2018-09-26

5.  Congenital granular cell tumor: Report of a case with literature review and differential diagnosis.

Authors:  Arpita Singh; Snehashish Ghosh; Anjani Kumar Yadav; Anuja Panthee
Journal:  Clin Case Rep       Date:  2022-03-13

6.  Multiple congenital epulis in alveolar ridges of maxilla and mandible in a newborn: a rare case report.

Authors:  Nader Saki; Somayeh Araghi
Journal:  Case Rep Otolaryngol       Date:  2014-04-08

7.  Congenital granular cell tumor in newborn.

Authors:  Tamer Zerener; Metin Sencimen; Ceyhan Altun; Hasan Ayberk Altug
Journal:  Eur J Dent       Date:  2013-10
  7 in total

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