Literature DB >> 19262106

Unfinished business: Incomplete laminin processing exposes a tumor target.

Jacqueline Banyard1.   

Abstract

The G45 domain of laminin-332 is cleaved in normal tissues but remains in squamous cell carcinomas. Targeting this domain using a G45 antibody reduced in vivo tumor growth and invasion and suggests a role for G45 as a new therapeutic target.

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Year:  2008        PMID： 19262106      PMCID： PMC2634984          DOI： 10.4161/cam.2.2.6483

Source DB:  PubMed          Journal:  Cell Adh Migr        ISSN： 1933-6918            Impact factor:   3.405


  3 in total

Review 1.  Form and function: the laminin family of heterotrimers.

Authors:  H Colognato; P D Yurchenco
Journal:  Dev Dyn       Date:  2000-06       Impact factor: 3.780

Review 2.  Tumour microenvironment: laminin 332 in squamous-cell carcinoma.

Authors:  M Peter Marinkovich
Journal:  Nat Rev Cancer       Date:  2007-05       Impact factor: 60.716

3.  Targeting a tumor-specific laminin domain critical for human carcinogenesis.

Authors:  Mark Tran; Patricia Rousselle; Pasi Nokelainen; Sruthi Tallapragada; Ngon T Nguyen; Edgar F Fincher; M Peter Marinkovich
Journal:  Cancer Res       Date:  2008-04-15       Impact factor: 12.701
  3 in total

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