BACKGROUND: The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated. METHODS AND RESULTS: Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient. CONCLUSIONS: OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary.
BACKGROUND: The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated. METHODS AND RESULTS: Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient. CONCLUSIONS: OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary.
Authors: Ki Hong Lee; Hyung Wook Park; Jeong Nam Eun; Jeong Gwan Cho; Nam Sik Yoon; Mi Ran Kim; Yo Han Ku; Hyukjin Park; Seung Hun Lee; Jeong Han Kim; Min Chul Kim; Woo Jin Kim; Hyun Kuk Kim; Jae Yeong Cho; Keun-Ho Park; Doo Sun Sim; Hyun Ju Yoon; Kye Hun Kim; Young Joon Hong; Ju Han Kim; Youngkeun Ahn; Myung Ho Jeong; Jong Chun Park Journal: Korean J Intern Med Date: 2017-08-11 Impact factor: 2.884