Literature DB >> 19261717

SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans.

Francesco Piva1, Matteo Giulietti, Linda Nocchi, Giovanni Principato.   

Abstract

UNLABELLED: The correct post-transcriptional RNA processing is finely regulated by RNA-binding proteins. Unfortunately, there is little experimental information on target RNA sequences of RNA-binding proteins and moreover such experimentally derived target sequences are annotated in a compact form by the score matrices that overestimate the number of possible recognized sequences. We carried out an exhaustive hand curated literature search to create a database, SpliceAid, collecting all the experimentally assessed target RNA sequences that are bound by splicing proteins in humans. We built a web resource, database driven, to easy query SpliceAid and give back the results by an accurate and dynamic graphic representation. AVAILABILITY: SpliceAid database is freely accessible at http://www.introni.it/splicing.html.

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Year:  2009        PMID: 19261717     DOI: 10.1093/bioinformatics/btp124

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  51 in total

1.  Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia.

Authors:  Mayumi Yoshida; Naoyuki Kataoka; Kenjyo Miyauchi; Kenji Ohe; Kei Iida; Suguru Yoshida; Takayuki Nojima; Yukiko Okuno; Hiroshi Onogi; Tomomi Usui; Akihide Takeuchi; Takamitsu Hosoya; Tsutomu Suzuki; Masatoshi Hagiwara
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-09       Impact factor: 11.205

2.  Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.

Authors:  Ryan M Smith; Audrey C Papp; Amy Webb; Cara L Ruble; Leanne M Munsie; Laura K Nisenbaum; Joel E Kleinman; Barbara K Lipska; Wolfgang Sadee
Journal:  Biol Psychiatry       Date:  2012-11-13       Impact factor: 13.382

3.  Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR).

Authors:  Oz Solomon; Shirley Oren; Michal Safran; Naamit Deshet-Unger; Pinchas Akiva; Jasmine Jacob-Hirsch; Karen Cesarkas; Reut Kabesa; Ninette Amariglio; Ron Unger; Gideon Rechavi; Eran Eyal
Journal:  RNA       Date:  2013-03-08       Impact factor: 4.942

4.  Alternative splicing reverses the cell-intrinsic and cell-extrinsic pro-oncogenic potentials of YAP1.

Authors:  Chi Ben; Xiaojing Wu; Atsushi Takahashi-Kanemitsu; Christopher Takaya Knight; Takeru Hayashi; Masanori Hatakeyama
Journal:  J Biol Chem       Date:  2020-08-06       Impact factor: 5.157

5.  A novel splicing silencer generated by DMD exon 45 deletion junction could explain upstream exon 44 skipping that modifies dystrophinopathy.

Authors:  Ery Kus Dwianingsih; Rusdy Ghazali Malueka; Atsushi Nishida; Kyoko Itoh; Tomoko Lee; Mariko Yagi; Kazumoto Iijima; Yasuhiro Takeshima; Masafumi Matsuo
Journal:  J Hum Genet       Date:  2014-05-29       Impact factor: 3.172

6.  IntSplice: prediction of the splicing consequences of intronic single-nucleotide variations in the human genome.

Authors:  Akihide Shibata; Tatsuya Okuno; Mohammad Alinoor Rahman; Yoshiteru Azuma; Jun-Ichi Takeda; Akio Masuda; Duygu Selcen; Andrew G Engel; Kinji Ohno
Journal:  J Hum Genet       Date:  2016-03-24       Impact factor: 3.172

7.  How is Herstatin, a tumor suppressor splice variant of the oncogene HER2, regulated?

Authors:  Marco Silipo; Hannah Gautrey; Swapna Satam; Thomas Lennard; Alison Tyson-Capper
Journal:  RNA Biol       Date:  2016-12-09       Impact factor: 4.652

8.  Identification of prognostic alternative splicing signatures in uveal melanoma.

Authors:  Xinyi Xie; Xinhua Zheng; Tianhua Xie; Jiping Cai; Yong Yao
Journal:  Int Ophthalmol       Date:  2021-01-21       Impact factor: 2.031

9.  Fine-scale variation and genetic determinants of alternative splicing across individuals.

Authors:  Jasmin Coulombe-Huntington; Kevin C L Lam; Christel Dias; Jacek Majewski
Journal:  PLoS Genet       Date:  2009-12-11       Impact factor: 5.917

10.  Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function.

Authors:  Silvia Lombardi; Gabriele Leo; Simone Merlin; Antonia Follenzi; John H McVey; Iva Maestri; Francesco Bernardi; Mirko Pinotti; Dario Balestra
Journal:  Am J Hum Genet       Date:  2021-07-08       Impact factor: 11.025

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